Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LUY98_RS14125 Genome accession   NZ_CP089497
Coordinates   2855988..2856704 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 3045_IIV_ST8     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2850988..2861704
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUY98_RS14105 - 2852080..2853030 (+) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -
  LUY98_RS14110 - 2853179..2854663 (+) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  LUY98_RS14115 - 2854660..2855619 (+) 960 WP_001253296.1 carbohydrate kinase -
  LUY98_RS14120 - 2855809..2855916 (-) 108 WP_031785433.1 hypothetical protein -
  LUY98_RS14125 agrA 2855988..2856704 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  LUY98_RS14130 agrC 2856723..2858015 (-) 1293 WP_029657921.1 quorum-sensing sensor histidine kinase AgrC -
  LUY98_RS14135 agrD 2858040..2858180 (-) 141 WP_001094304.1 cyclic lactone autoinducer peptide AgrD -
  LUY98_RS14140 - 2858182..2858745 (-) 564 WP_001105715.1 accessory gene regulator AgrB -
  LUY98_RS14145 hld 2859035..2859115 (+) 81 WP_000046022.1 delta-hemolysin -
  LUY98_RS14150 - 2859715..2860500 (-) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  LUY98_RS14155 - 2860860..2861486 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=637585 LUY98_RS14125 WP_000688492.1 2855988..2856704(-) (agrA) [Staphylococcus aureus strain 3045_IIV_ST8]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=637585 LUY98_RS14125 WP_000688492.1 2855988..2856704(-) (agrA) [Staphylococcus aureus strain 3045_IIV_ST8]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1