Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LUY98_RS00460 Genome accession   NZ_CP089497
Coordinates   82179..82808 (+) Length   209 a.a.
NCBI ID   WP_061843483.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 3045_IIV_ST8     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 77179..87808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUY98_RS00435 - 77499..78485 (-) 987 WP_000999711.1 aromatic acid exporter family protein -
  LUY98_RS00440 map 79072..79830 (+) 759 WP_000636137.1 type I methionyl aminopeptidase -
  LUY98_RS00445 - 80047..80433 (+) 387 WP_001110183.1 hypothetical protein -
  LUY98_RS00450 liaF 80448..81149 (+) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  LUY98_RS00455 vraS 81146..82189 (+) 1044 WP_001017129.1 sensor histidine kinase Regulator
  LUY98_RS00460 vraR 82179..82808 (+) 630 WP_061843483.1 two-component system response regulator VraR Regulator
  LUY98_RS00465 - 82921..84138 (-) 1218 WP_000037083.1 YihY/virulence factor BrkB family protein -
  LUY98_RS00470 - 84416..84691 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  LUY98_RS00475 - 84698..85162 (-) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  LUY98_RS00480 - 85309..85509 (+) 201 WP_001813025.1 DUF1128 family protein -
  LUY98_RS00485 - 85512..86768 (+) 1257 WP_001793428.1 aminopeptidase -
  LUY98_RS00490 - 86858..87388 (+) 531 WP_000184383.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23589.35 Da        Isoelectric Point: 5.3935

>NTDB_id=637545 LUY98_RS00460 WP_061843483.1 82179..82808(+) (vraR) [Staphylococcus aureus strain 3045_IIV_ST8]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDTGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=637545 LUY98_RS00460 WP_061843483.1 82179..82808(+) (vraR) [Staphylococcus aureus strain 3045_IIV_ST8]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCACATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATACAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGTGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.522

100

0.995
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378