Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   LUZ06_RS10415 Genome accession   NZ_CP089493
Coordinates   2087784..2089133 (+) Length   449 a.a.
NCBI ID   WP_061731575.1    Uniprot ID   B4F4B7
Organism   Staphylococcus aureus strain 0308_IA_ST247     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2082784..2094133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ06_RS10400 - 2083323..2084093 (-) 771 WP_000767841.1 DUF6414 family protein -
  LUZ06_RS10405 - 2084210..2085640 (+) 1431 WP_001008608.1 DUF6038 family protein -
  LUZ06_RS10410 cch1 2085760..2087550 (+) 1791 WP_061731576.1 cassette chromosome replicative helicase -
  LUZ06_RS10415 ccrA 2087784..2089133 (+) 1350 WP_061731575.1 cassette chromosome recombinase CcrA Machinery gene
  LUZ06_RS10420 ccrB 2089155..2090783 (+) 1629 WP_001186602.1 cassette chromosome recombinase CcrB Machinery gene
  LUZ06_RS10425 - 2091301..2091651 (+) 351 WP_000859155.1 SAUGI family uracil-DNA glycosylase inhibitor -
  LUZ06_RS10430 - 2091738..2092049 (+) 312 WP_000700853.1 DUF960 family protein -
  LUZ06_RS10435 - 2092067..2092573 (+) 507 WP_001092169.1 DUF1643 domain-containing protein -
  LUZ06_RS10440 - 2092594..2092911 (+) 318 WP_000659050.1 JAB domain-containing protein -
  LUZ06_RS10445 - 2093030..2094115 (+) 1086 WP_000868132.1 tyrosine-type recombinase/integrase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52557.24 Da        Isoelectric Point: 9.9150

>NTDB_id=637490 LUZ06_RS10415 WP_061731575.1 2087784..2089133(+) (ccrA) [Staphylococcus aureus strain 0308_IA_ST247]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVKNGLQEKAKQGQLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIMNPNYCGRVINQYGQFDNMFPSIVSANV
YEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=637490 LUZ06_RS10415 WP_061731575.1 2087784..2089133(+) (ccrA) [Staphylococcus aureus strain 0308_IA_ST247]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACTTATCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCAGATAATATTGGAGAAC
AAGTCAAAAATGGCCTTCAAGAAAAGGCAAAACAAGGTCAATTGATTACAACACATGCGCCTTTTGGTTACGACTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCTTATCAAGTTCGTAATATTATCATGA
ACCCTAATTATTGTGGTCGTGTTATCAACCAATACGGTCAATTCGACAATATGTTCCCTTCTATTGTTTCAGCAAATGTA
TATGAACAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAATATGAATGCTTCACGCTTTGTCTGTGATTTCAAAGGCATCAATGCACAGACATTGGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterProScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-248)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

96.659

100

0.967
  ccrA Staphylococcus aureus COL

75.056

100

0.751