Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   LUZ06_RS04505 Genome accession   NZ_CP089493
Coordinates   893720..894406 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 0308_IA_ST247     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 888720..899406
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ06_RS04485 rpsT 889634..889885 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  LUZ06_RS04490 holA 889930..890904 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  LUZ06_RS04495 comEC 890961..893162 (-) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LUZ06_RS04500 - 893167..893628 (-) 462 WP_000439693.1 ComE operon protein 2 -
  LUZ06_RS04505 comEA 893720..894406 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  LUZ06_RS04510 - 894446..895162 (-) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  LUZ06_RS04515 rsfS 895165..895518 (-) 354 WP_001088022.1 ribosome silencing factor -
  LUZ06_RS04520 yqeK 895519..896103 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  LUZ06_RS04525 nadD 896093..896662 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  LUZ06_RS04530 yhbY 896665..896955 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  LUZ06_RS04535 aroE 896959..897765 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  LUZ06_RS04540 yqeH 897779..898879 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=637476 LUZ06_RS04505 WP_001792568.1 893720..894406(-) (comEA) [Staphylococcus aureus strain 0308_IA_ST247]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=637476 LUZ06_RS04505 WP_001792568.1 893720..894406(-) (comEA) [Staphylococcus aureus strain 0308_IA_ST247]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969