Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LUY97_RS14635 Genome accession   NZ_CP089483
Coordinates   2912371..2913087 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 0104_III_ST239     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2907371..2918087
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUY97_RS14615 - 2908465..2909415 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  LUY97_RS14620 - 2909564..2911048 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  LUY97_RS14625 - 2911045..2912004 (+) 960 WP_001253312.1 carbohydrate kinase -
  LUY97_RS14630 - 2912192..2912299 (-) 108 WP_001790167.1 hypothetical protein -
  LUY97_RS14635 agrA 2912371..2913087 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  LUY97_RS14640 agrC 2913106..2914398 (-) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  LUY97_RS14645 agrD 2914423..2914563 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  LUY97_RS14650 agrB 2914560..2915129 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  LUY97_RS14655 hld 2915419..2915499 (+) 81 WP_000046022.1 delta-hemolysin -
  LUY97_RS14660 - 2916096..2916881 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  LUY97_RS14665 - 2917242..2917868 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=637281 LUY97_RS14635 WP_000688492.1 2912371..2913087(-) (agrA) [Staphylococcus aureus strain 0104_III_ST239]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=637281 LUY97_RS14635 WP_000688492.1 2912371..2913087(-) (agrA) [Staphylococcus aureus strain 0104_III_ST239]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1