Detailed information NTG0063697

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: U063_RS03420
• Genome accession: NC_022886
• Coordinates: 669580..670380 (+)
• Length: 266 a.a.
• NCBI ID: WP_023591965.1
• Uniprot ID: V5NN53
• Organism: Helicobacter pylori BM012A
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 664580..675380

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U063_RS03385 (U063_0669)	pseH	665074..665616 (+)	543	WP_023591961.1	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	-
U063_RS03390 (U063_0670)	-	665549..666487 (-)	939	WP_023591962.1	tetraacyldisaccharide 4'-kinase	-
U063_RS03395 (U063_0671)	-	666484..667266 (-)	783	WP_023591963.1	NAD+ synthase	-
U063_RS03405 (U063_0673)	ilvC	667516..668508 (+)	993	WP_023591964.1	ketol-acid reductoisomerase	-
U063_RS03410 (U063_0674)	minD	668532..669338 (+)	807	WP_023526244.1	septum site-determining protein MinD	-
U063_RS03415 (U063_0675)	minE	669335..669568 (+)	234	WP_000118278.1	cell division topological specificity factor MinE	-
U063_RS03420 (U063_0676)	dprA	669580..670380 (+)	801	WP_023591965.1	DNA-processing protein DprA	Machinery gene
U063_RS03425 (U063_0677)	dprB	670377..670781 (+)	405	WP_038419820.1	Holliday junction resolvase RuvX	Machinery gene
U063_RS03430 (U063_0679)	-	670913..671191 (+)	279	WP_023591968.1	tetratricopeptide repeat protein	-
U063_RS08380 (U063_0680)	-	671169..671666 (+)	498	Protein_653	AAA family ATPase	-
U063_RS08860	-	671669..671872 (+)	204	WP_080261063.1	hypothetical protein	-
U063_RS08865 (U063_0681)	-	671884..672582 (+)	699	WP_226975758.1	DUF1887 domain-containing protein	-
U063_RS08390 (U063_0683)	-	672832..672954 (+)	123	Protein_656	type II restriction endonuclease	-
U063_RS08725 (U063_0684)	-	673105..673319 (-)	215	Protein_657	hypothetical protein	-
U063_RS03455 (U063_0685)	-	673365..673553 (-)	189	WP_023591972.1	hypothetical protein	-
U063_RS03460 (U063_0686)	mscS	673606..674430 (-)	825	WP_023591973.1	small-conductance mechanosensitive channel MscS	-
U063_RS08665	-	674580..674700 (-)	121	Protein_660	DNA adenine methylase	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29955.83 Da
• Isoelectric Point: 8.3904

>NTDB_id=63697 U063_RS03420 WP_023591965.1 669580..670380(+) (dprA) [Helicobacter pylori BM012A]
MKSHFQYSALENIPKAFDTLKDPPKKLYCVGDTKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGTVIVSGGALGV
DIIAQENALPKTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPIKGSFLARNRLVIALSDVVIIPQADLQSG
SMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDYHLKEMPEMKDEFLEYFAKNPSYEEAY
LKFGDKLLEYELLGKIKRINHLVVLA

Nucleotide

• Length: 801 bp

>NTDB_id=63697 U063_RS03420 WP_023591965.1 669580..670380(+) (dprA) [Helicobacter pylori BM012A]
ATGAAAAGCCACTTCCAATACAGCGCGCTAGAAAATATCCCTAAAGCCTTTGATACGCTCAAAGACCCCCCTAAAAAACT
CTATTGTGTGGGCGACACCAAGCTTTTAGAAGCGCCTTTAAAAGTGGCTATCATAGGCACAAGAAGACCCACCCCTTACA
GCAAGCAACACACGATCACTCTAGCCAGAGAGCTTGCTAAAAATGGCACGGTTATTGTGAGTGGGGGAGCGTTAGGAGTG
GATATTATCGCTCAAGAAAACGCCTTACCAAAAACGATCATGCTTTCGCCTTGCAGTTTGGATTTCATCTATCCTACGAA
CAACCATAAAGTGATCCAAGAAATCGCGCAAAACGGCCTGATTTTAAGCGAATATGAAAAAGACTTCATGCCCATTAAAG
GCTCTTTTTTAGCGAGAAACCGCCTAGTGATCGCTTTAAGCGATGTAGTGATTATCCCCCAAGCGGATTTACAAAGCGGC
TCTATGAGTAGCGCGAGATTAGCCCAAAAATACCAAAAACCCTTATTTGTTTTGCCTCAACGCCTGAATGAGAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTCAAAATTTTATAAACACCCTTTTAAAAGACT
ACCATTTAAAAGAAATGCCTGAAATGAAAGATGAATTTTTAGAATATTTTGCGAAAAACCCTAGCTATGAAGAGGCGTAT
CTCAAATTTGGGGATAAACTTTTAGAATACGAGCTGTTGGGTAAGATCAAGCGCATCAATCATCTCGTGGTGTTAGCGTG
A

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (11-197)

3D structure

• AlphaFold DB: V5NN53

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	96.617	100	0.966
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	47.345	84.962	0.402