Detailed information NTG0063692

Bioinformatically predicted

Overview

• Name: comB10
• Type: Machinery gene
• Locus tag: U063_RS00210
• Genome accession: NC_022886
• Coordinates: 39219..40355 (+)
• Length: 378 a.a.
• NCBI ID: WP_023591496.1
• Uniprot ID: V5NKS6
• Organism: Helicobacter pylori BM012A
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 34219..45355

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U063_RS00175 (U063_0035)	panD	34664..35017 (+)	354	WP_023591491.1	aspartate 1-decarboxylase	-
U063_RS00180 (U063_0036)	-	35020..35313 (+)	294	WP_000347917.1	YbaB/EbfC family nucleoid-associated protein	-
U063_RS00185 (U063_0037)	-	35313..36308 (+)	996	WP_041200974.1	PDZ domain-containing protein	-
U063_RS00190 (U063_0038)	comB6	36316..37371 (+)	1056	WP_023591493.1	P-type conjugative transfer protein TrbL	Machinery gene
U063_RS00195 (U063_0039)	comB7	37387..37500 (+)	114	WP_001217873.1	hypothetical protein	Machinery gene
U063_RS00200 (U063_0040)	comB8	37497..38240 (+)	744	WP_023591494.1	virB8 family protein	Machinery gene
U063_RS00205 (U063_0041)	comB9	38240..39226 (+)	987	WP_041200975.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
U063_RS00210 (U063_0042)	comB10	39219..40355 (+)	1137	WP_023591496.1	DNA type IV secretion system protein ComB10	Machinery gene
U063_RS00215 (U063_0043)	-	40426..41838 (+)	1413	WP_023591497.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
U063_RS00220 (U063_0044)	gmd	41868..43013 (+)	1146	WP_023591498.1	GDP-mannose 4,6-dehydratase	-
U063_RS00225 (U063_0045)	-	43006..43938 (+)	933	WP_023591499.1	GDP-L-fucose synthase	-
U063_RS08220 (U063_0046)	-	44328..44756 (-)	429	WP_080261117.1	hypothetical protein	-

Sequence

Protein

• Length: 378 a.a.
• Molecular weight: 42208.81 Da
• Isoelectric Point: 9.9637

>NTDB_id=63692 U063_RS00210 WP_023591496.1 39219..40355(+) (comB10) [Helicobacter pylori BM012A]
MNKWLKGVVVFVGGFATIVTISLVYHQKPKAPLNNQPSLLNDDEVKYPLQDYTFTQNPQPTNTESSKDATIKALQEQLKA
ALKALNSKEMNYSKEETFKSPPIDLKANTTPPKKDFSSKQWDLLAARITPFKQSPKNYEENLIFPMDNPKGIDGFTNLKE
KDIATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFAHMGKAVLIPKGSKVIGYYSNNNKMGEYRLDIVWS
RIITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGVPLLLSTLTNGLLIGITSALNNRGNKEGATNFFGDYLLMQL
MRQSGMGINQVVNQILRDKSKIAPIVVIREGSRVFISPNTDIFFPIPRENEVIAEFLK

Nucleotide

• Length: 1137 bp

>NTDB_id=63692 U063_RS00210 WP_023591496.1 39219..40355(+) (comB10) [Helicobacter pylori BM012A]
ATGAATAAGTGGCTTAAGGGGGTGGTTGTTTTTGTAGGGGGTTTTGCAACGATTGTAACAATTTCTTTAGTCTATCATCA
AAAGCCAAAAGCCCCCTTAAATAACCAACCTAGCCTTTTGAATGATGATGAGGTGAAATACCCCTTACAGGATTACACTT
TCACTCAAAACCCACAGCCAACCAACACGGAAAGCTCTAAAGACGCCACCATCAAAGCCTTACAAGAACAGCTCAAAGCC
GCTTTAAAAGCCCTAAACTCCAAAGAAATGAATTATTCCAAAGAAGAAACTTTTAAGAGCCCTCCCATAGATTTAAAAGC
AAATACAACCCCCCCTAAAAAAGACTTTTCTTCAAAGCAATGGGATTTACTAGCCGCTCGCATCACCCCTTTCAAACAAA
GCCCTAAAAATTACGAAGAAAACCTGATTTTCCCCATGGATAACCCTAAAGGCATTGATGGTTTCACTAACCTTAAAGAA
AAAGACATCGCCACCAATGAAAACAAGCTTTTACGCACCATTACAGCCGATAAAATGATACCCGCCTTTCTCATCACGCC
TATTTCTAGCCAGATCGCTGGTAAAGTCATCGCGCAAGTGGAGAGCGATATTTTTGCTCACATGGGCAAGGCCGTCTTAA
TCCCCAAAGGCTCTAAAGTCATAGGCTATTACAGCAACAACAACAAAATGGGCGAATACCGCTTGGATATTGTATGGAGC
CGCATCATCACCCCCCATGGCATCAATATCATGCTCACTAACGCTAAAGGGGCGGACATTAAAGGCTATAACGGCTTGGT
GGGGGAATTGATTGAAAGGAATTTCCAGCGCTATGGCGTGCCGTTACTGCTTTCTACTCTCACTAACGGCTTGTTGATTG
GGATCACTTCGGCTTTAAACAACAGGGGCAATAAAGAAGGAGCCACCAATTTCTTTGGGGATTATCTTTTAATGCAATTG
ATGAGGCAAAGCGGCATGGGGATCAATCAAGTGGTCAATCAAATTTTAAGAGACAAGAGCAAAATCGCTCCTATTGTGGT
GATTAGAGAGGGAAGTAGGGTTTTCATTTCGCCCAATACTGACATATTCTTTCCTATACCCAGAGAGAATGAAGTCATCG
CTGAGTTTTTGAAGTGA

Domains

Predicted by InterproScan.

• Bacterial conjugation TrbI-like protein (TrbI) (173-364)

3D structure

• AlphaFold DB: V5NKS6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB10	Helicobacter pylori P1	97.619	100	0.976