Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   U063_RS00200 Genome accession   NC_022886
Coordinates   37497..38240 (+) Length   247 a.a.
NCBI ID   WP_023591494.1    Uniprot ID   -
Organism   Helicobacter pylori BM012A     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32497..43240
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U063_RS00175 (U063_0035) panD 34664..35017 (+) 354 WP_023591491.1 aspartate 1-decarboxylase -
  U063_RS00180 (U063_0036) - 35020..35313 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  U063_RS00185 (U063_0037) - 35313..36308 (+) 996 WP_041200974.1 PDZ domain-containing protein -
  U063_RS00190 (U063_0038) comB6 36316..37371 (+) 1056 WP_023591493.1 P-type conjugative transfer protein TrbL Machinery gene
  U063_RS00195 (U063_0039) comB7 37387..37500 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  U063_RS00200 (U063_0040) comB8 37497..38240 (+) 744 WP_023591494.1 virB8 family protein Machinery gene
  U063_RS00205 (U063_0041) comB9 38240..39226 (+) 987 WP_041200975.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  U063_RS00210 (U063_0042) comB10 39219..40355 (+) 1137 WP_023591496.1 DNA type IV secretion system protein ComB10 Machinery gene
  U063_RS00215 (U063_0043) - 40426..41838 (+) 1413 WP_023591497.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  U063_RS00220 (U063_0044) gmd 41868..43013 (+) 1146 WP_023591498.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28639.85 Da        Isoelectric Point: 8.9546

>NTDB_id=63690 U063_RS00200 WP_023591494.1 37497..38240(+) (comB8) [Helicobacter pylori BM012A]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=63690 U063_RS00200 WP_023591494.1 37497..38240(+) (comB8) [Helicobacter pylori BM012A]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCAGTGAGTGATTTGGACATGCAAAGCGTGTTTCGGTTGGAAAGAAACCGCTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATTGTTTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGAGCGTATGTGTTGAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAGGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCACAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCCATTGCCGCTAAACTTTTGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTCACCCGCTACAGCATCACTGAAATT
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.976

100

0.98

Multiple sequence alignment