Detailed information NTG0636663

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: LLE34_RS10255
• Genome accession: NZ_CP106769
• Coordinates: 1941346..1942572 (+)
• Length: 408 a.a.
• NCBI ID: WP_229944428.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain 10524
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1936346..1947572

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLE34_RS10225 (LLE34_10225)	-	1937228..1937506 (-)	279	WP_263070674.1	hypothetical protein	-
LLE34_RS10230 (LLE34_10230)	dksA	1937521..1937937 (-)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-
LLE34_RS10235 (LLE34_10235)	proC	1938086..1938877 (-)	792	WP_003694504.1	pyrroline-5-carboxylate reductase	-
LLE34_RS10240 (LLE34_10240)	-	1938926..1939333 (-)	408	WP_003690202.1	hypothetical protein	-
LLE34_RS10245 (LLE34_10245)	-	1939333..1940019 (-)	687	WP_003692103.1	YggS family pyridoxal phosphate-dependent enzyme	-
LLE34_RS10250 (LLE34_10250)	pilT	1940139..1941182 (+)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
LLE34_RS10255 (LLE34_10255)	pilU	1941346..1942572 (+)	1227	WP_229944428.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
LLE34_RS10260 (LLE34_10260)	yccS	1942689..1944839 (+)	2151	WP_003692098.1	YccS family putative transporter	-
LLE34_RS10265 (LLE34_10265)	-	1945321..1945605 (-)	285	WP_003692093.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45697.34 Da
• Isoelectric Point: 7.5293

>NTDB_id=636663 LLE34_RS10255 WP_229944428.1 1941346..1942572(+) (pilU) [Neisseria gonorrhoeae strain 10524]
MNTDNLHDILDETVQVYSQKKQSRSETPAEIGTHFHPLLDRLCETAEAQNASNILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYYSQGSAGLVLRRINHVIPQMRELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=636663 LLE34_RS10255 WP_229944428.1 1941346..1942572(+) (pilU) [Neisseria gonorrhoeae strain 10524]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCACACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCAACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACTACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCGGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAGGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGACCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (79-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.598	88.48	0.395
pilU	Pseudomonas stutzeri DSM 10701	44.944	87.255	0.392
pilU	Vibrio cholerae strain A1552	46.726	82.353	0.385