Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LTK15_RS01410 Genome accession   NZ_CP089154
Coordinates   261162..261791 (+) Length   209 a.a.
NCBI ID   WP_086040686.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UNC_SaCF36     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 256162..266791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LTK15_RS01385 (LTK15_01385) - 256538..257524 (-) 987 WP_000999713.1 aromatic acid exporter family protein -
  LTK15_RS01390 (LTK15_01390) map 258055..258813 (+) 759 WP_000636137.1 type I methionyl aminopeptidase -
  LTK15_RS01395 (LTK15_01395) - 259030..259416 (+) 387 WP_001110184.1 hypothetical protein -
  LTK15_RS01400 (LTK15_01400) liaF 259431..260132 (+) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  LTK15_RS01405 (LTK15_01405) vraS 260129..261172 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  LTK15_RS01410 (LTK15_01410) vraR 261162..261791 (+) 630 WP_086040686.1 two-component system response regulator VraR Regulator
  LTK15_RS01415 (LTK15_01415) - 261904..263121 (-) 1218 WP_000037083.1 YihY/virulence factor BrkB family protein -
  LTK15_RS01420 (LTK15_01420) - 263399..263674 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  LTK15_RS01425 (LTK15_01425) - 263681..264145 (-) 465 WP_000228668.1 low molecular weight protein-tyrosine-phosphatase -
  LTK15_RS01430 (LTK15_01430) - 264292..264492 (+) 201 WP_000180459.1 DUF1128 family protein -
  LTK15_RS01435 (LTK15_01435) - 264504..265751 (+) 1248 WP_232044296.1 aminopeptidase -
  LTK15_RS01440 (LTK15_01440) - 265841..266371 (+) 531 WP_000184383.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23589.35 Da        Isoelectric Point: 5.3935

>NTDB_id=635348 LTK15_RS01410 WP_086040686.1 261162..261791(+) (vraR) [Staphylococcus aureus strain UNC_SaCF36]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKTHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=635348 LTK15_RS01410 WP_086040686.1 261162..261791(+) (vraR) [Staphylococcus aureus strain UNC_SaCF36]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAACACATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGTGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.522

100

0.995
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373