Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   LSP18_RS23565 Genome accession   NZ_CP089063
Coordinates   5039139..5040476 (+) Length   445 a.a.
NCBI ID   WP_043556106.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain UNC_PaerCF37     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5034139..5045476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LSP18_RS23540 (LSP18_23760) pgeF 5034282..5035010 (-) 729 WP_003102588.1 peptidoglycan editing factor PgeF -
  LSP18_RS23545 (LSP18_23765) rluD 5035007..5035969 (-) 963 WP_003094686.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  LSP18_RS23550 (LSP18_23770) - 5036115..5037140 (+) 1026 WP_003102590.1 outer membrane protein assembly factor BamD -
  LSP18_RS23555 (LSP18_23775) - 5037297..5037542 (+) 246 WP_003102591.1 PP0621 family protein -
  LSP18_RS23560 (LSP18_23780) pilS 5037532..5039124 (+) 1593 WP_003110428.1 two-component system sensor histidine kinase PilS Regulator
  LSP18_RS23565 (LSP18_23785) pilR 5039139..5040476 (+) 1338 WP_043556106.1 two-component system response regulator PilR Regulator
  LSP18_RS23570 (LSP18_23790) thiO 5040522..5041616 (-) 1095 WP_031671383.1 glycine oxidase ThiO -
  LSP18_RS23575 (LSP18_23795) - 5041751..5042260 (+) 510 WP_003102595.1 Tfp pilus assembly protein FimT/FimU -
  LSP18_RS23580 (LSP18_23800) - 5042366..5042872 (+) 507 WP_003102598.1 Tfp pilus assembly protein FimT/FimU -
  LSP18_RS23585 (LSP18_23805) pilV 5042863..5043420 (+) 558 WP_003119423.1 type 4a pilus minor pilin PilV Machinery gene
  LSP18_RS23590 (LSP18_23810) pilW 5043417..5044241 (+) 825 WP_003119422.1 type 4a pilus minor pilin PilW -
  LSP18_RS23595 (LSP18_23815) pilX 5044238..5044825 (+) 588 WP_003112826.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49727.02 Da        Isoelectric Point: 5.8654

>NTDB_id=634993 LSP18_RS23565 WP_043556106.1 5039139..5040476(+) (pilR) [Pseudomonas aeruginosa strain UNC_PaerCF37]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADASGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=634993 LSP18_RS23565 WP_043556106.1 5039139..5040476(+) (pilR) [Pseudomonas aeruginosa strain UNC_PaerCF37]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGTCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAAGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Response regulator receiver domain (Response_reg)

(7-115)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.775

100

0.998
  pilR Acinetobacter baumannii strain A118

51.198

100

0.528