Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CSB63_RS10035 Genome accession   NZ_CP089060
Coordinates   748378..748464 (+) Length   28 a.a.
NCBI ID   WP_420910722.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CH8     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 743378..753464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSB63_RS04085 (CSB63_0806) - 744337..744909 (-) 573 WP_041827006.1 ECF transporter S component -
  CSB63_RS04090 (CSB63_0807) coaC 744937..745482 (-) 546 WP_014608202.1 phosphopantothenoylcysteine decarboxylase -
  CSB63_RS04095 (CSB63_0808) - 745475..746158 (-) 684 WP_002948206.1 phosphopantothenate--cysteine ligase -
  CSB63_RS04100 (CSB63_0809) - 746352..748022 (+) 1671 WP_113870374.1 formate--tetrahydrofolate ligase -
  CSB63_RS10030 (CSB63_0810) - 748208..748357 (+) 150 Protein_745 DNA-binding response regulator -
  CSB63_RS10035 ciaR 748378..748464 (+) 87 WP_420910722.1 hypothetical protein Regulator
  CSB63_RS04110 (CSB63_0811) - 748454..748753 (+) 300 WP_022096598.1 hypothetical protein -
  CSB63_RS04115 - 748837..749872 (+) 1036 Protein_748 sensor histidine kinase -
  CSB63_RS04120 (CSB63_0813) rpsT 749961..750197 (-) 237 WP_002947597.1 30S ribosomal protein S20 -
  CSB63_RS04125 (CSB63_0814) coaA 750266..751186 (-) 921 WP_002947590.1 type I pantothenate kinase -
  CSB63_RS04130 - 751512..752101 (+) 590 Protein_751 class I SAM-dependent methyltransferase -
  CSB63_RS04135 - 752098..753372 (+) 1275 Protein_752 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 28 a.a.        Molecular weight: 3182.73 Da        Isoelectric Point: 10.8472

>NTDB_id=634899 CSB63_RS10035 WP_420910722.1 748378..748464(+) (ciaR) [Streptococcus thermophilus strain CH8]
MRKKLKGTDFATNLQTLRSVGYILKNAD

Nucleotide


Download         Length: 87 bp        

>NTDB_id=634899 CSB63_RS10035 WP_420910722.1 748378..748464(+) (ciaR) [Streptococcus thermophilus strain CH8]
ATTCGTAAGAAACTTAAGGGGACTGATTTTGCTACCAACCTACAAACCTTAAGAAGTGTGGGGTATATTTTGAAGAATGC
TGACTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

77.778

96.429

0.75
  ciaR Streptococcus pneumoniae D39

77.778

96.429

0.75
  ciaR Streptococcus pneumoniae R6

77.778

96.429

0.75
  ciaR Streptococcus pneumoniae TIGR4

77.778

96.429

0.75
  ciaR Streptococcus mutans UA159

75

100

0.75