Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   CSB63_RS05530 Genome accession   NZ_CP089060
Coordinates   1024088..1025428 (-) Length   446 a.a.
NCBI ID   WP_134973270.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CH8     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1019088..1030428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSB63_RS05500 (CSB63_1138) - 1019208..1019594 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  CSB63_RS05505 - 1019686..1020564 (-) 879 Protein_1026 GNAT family N-acetyltransferase -
  CSB63_RS05510 (CSB63_1141) yidA 1020772..1021581 (+) 810 WP_011226081.1 sugar-phosphatase -
  CSB63_RS05515 (CSB63_1142) - 1021583..1022797 (+) 1215 WP_002953123.1 aminoacyltransferase -
  CSB63_RS05520 - 1022849..1023210 (-) 362 Protein_1029 YbaN family protein -
  CSB63_RS05525 (CSB63_1144) vicX 1023270..1024079 (-) 810 WP_024704147.1 MBL fold metallo-hydrolase Regulator
  CSB63_RS05530 (CSB63_1145) vicK 1024088..1025428 (-) 1341 WP_134973270.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CSB63_RS05535 (CSB63_1146) vicR 1025421..1026128 (-) 708 WP_011681206.1 response regulator YycF Regulator
  CSB63_RS05540 (CSB63_1147) - 1026655..1027422 (+) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  CSB63_RS05545 (CSB63_1148) - 1027434..1028267 (+) 834 WP_134973271.1 transporter substrate-binding domain-containing protein -
  CSB63_RS05550 (CSB63_1149) - 1028285..1028983 (+) 699 WP_014608374.1 amino acid ABC transporter permease -
  CSB63_RS05555 (CSB63_1150) - 1028995..1029645 (+) 651 WP_014608375.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50805.03 Da        Isoelectric Point: 5.2465

>NTDB_id=634870 CSB63_RS05530 WP_134973270.1 1024088..1025428(-) (vicK) [Streptococcus thermophilus strain CH8]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLRIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGRSYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGQITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=634870 CSB63_RS05530 WP_134973270.1 1024088..1025428(-) (vicK) [Streptococcus thermophilus strain CH8]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAGGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCGTAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGCAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGGTCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.825

0.684
  micB Streptococcus pneumoniae Cp1015

65.82

97.085

0.639