Detailed information NTG0634871

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: CSB63_RS05535
• Genome accession: NZ_CP089060
• Coordinates: 1025421..1026128 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CH8
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1020421..1031128

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSB63_RS05510 (CSB63_1141)	yidA	1020772..1021581 (+)	810	WP_011226081.1	sugar-phosphatase	-
CSB63_RS05515 (CSB63_1142)	-	1021583..1022797 (+)	1215	WP_002953123.1	aminoacyltransferase	-
CSB63_RS05520	-	1022849..1023210 (-)	362	Protein_1029	YbaN family protein	-
CSB63_RS05525 (CSB63_1144)	vicX	1023270..1024079 (-)	810	WP_024704147.1	MBL fold metallo-hydrolase	Regulator
CSB63_RS05530 (CSB63_1145)	vicK	1024088..1025428 (-)	1341	WP_134973270.1	cell wall metabolism sensor histidine kinase VicK	Regulator
CSB63_RS05535 (CSB63_1146)	vicR	1025421..1026128 (-)	708	WP_011681206.1	response regulator YycF	Regulator
CSB63_RS05540 (CSB63_1147)	-	1026655..1027422 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
CSB63_RS05545 (CSB63_1148)	-	1027434..1028267 (+)	834	WP_134973271.1	transporter substrate-binding domain-containing protein	-
CSB63_RS05550 (CSB63_1149)	-	1028285..1028983 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
CSB63_RS05555 (CSB63_1150)	-	1028995..1029645 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
CSB63_RS05560 (CSB63_1151)	endA	1029716..1030597 (-)	882	WP_111679622.1	DNA/RNA non-specific endonuclease	Machinery gene
CSB63_RS05565 (CSB63_1152)	-	1030659..1030847 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=634871 CSB63_RS05535 WP_011681206.1 1025421..1026128(-) (vicR) [Streptococcus thermophilus strain CH8]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=634871 CSB63_RS05535 WP_011681206.1 1025421..1026128(-) (vicR) [Streptococcus thermophilus strain CH8]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387