Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LPC11_RS04690 Genome accession   NZ_CP088218
Coordinates   976632..977261 (+) Length   209 a.a.
NCBI ID   WP_002466112.1    Uniprot ID   -
Organism   Staphylococcus sp. HL28     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 971632..982261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPC11_RS04660 (LPC11_04660) - 971656..972381 (+) 726 WP_023373124.1 type 1 glutamine amidotransferase -
  LPC11_RS04665 (LPC11_04665) - 972448..973434 (-) 987 WP_023373122.1 aromatic acid exporter family protein -
  LPC11_RS04670 (LPC11_04670) map 973601..974356 (+) 756 WP_023373120.1 type I methionyl aminopeptidase -
  LPC11_RS04675 (LPC11_04675) - 974500..974886 (+) 387 WP_023373118.1 DUF2543 family protein -
  LPC11_RS04680 (LPC11_04680) liaF 974901..975602 (+) 702 WP_023373116.1 cell wall-active antibiotics response protein LiaF -
  LPC11_RS04685 (LPC11_04685) vraS 975599..976642 (+) 1044 WP_002452288.1 sensor histidine kinase Regulator
  LPC11_RS04690 (LPC11_04690) vraR 976632..977261 (+) 630 WP_002466112.1 two-component system response regulator VraR Regulator
  LPC11_RS04695 (LPC11_04695) - 977320..978555 (-) 1236 WP_023373114.1 YihY/virulence factor BrkB family protein -
  LPC11_RS04700 (LPC11_04700) - 978783..979067 (-) 285 WP_002466132.1 YtxH domain-containing protein -
  LPC11_RS04705 (LPC11_04705) - 979074..979538 (-) 465 WP_023373112.1 low molecular weight protein-tyrosine-phosphatase -
  LPC11_RS04710 (LPC11_04710) - 979685..979888 (+) 204 WP_041613607.1 DUF1128 domain-containing protein -
  LPC11_RS04715 (LPC11_04715) - 979901..981142 (+) 1242 WP_023373108.1 aminopeptidase -
  LPC11_RS04720 (LPC11_04720) - 981201..981731 (+) 531 WP_023373106.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23562.15 Da        Isoelectric Point: 4.7945

>NTDB_id=633313 LPC11_RS04690 WP_002466112.1 976632..977261(+) (vraR) [Staphylococcus sp. HL28]
MAIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGESGKDAIAKAHELQPDLILMDLLMDDMDGVEATTEIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYNGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=633313 LPC11_RS04690 WP_002466112.1 976632..977261(+) (vraR) [Staphylococcus sp. HL28]
ATGGCGATTAAAGTATTATTTGTAGATGACCATGAGATGGTTAGAATAGGTATATCAAGTTACTTATCAACTCAATCTGA
CATTGAAGTAGTGGGAGAAGGAGAGTCTGGGAAAGATGCAATTGCTAAGGCACATGAGTTACAACCAGATTTAATTCTAA
TGGACTTACTGATGGATGATATGGATGGGGTAGAAGCGACAACAGAAATAAAAAAGGATTTACCTCACATCAAAGTAGTG
ATGCTTACAAGTTTCATTGAAGATAAAGAAGTGTATCGAGCTCTAGATGCTGGTGTAGATAGTTATATATTAAAGACTAC
AAGTGCTAGTGATATTGCAGAAGCGGTTCGTAAAACATATAATGGTGAATCGGTGTTTGAACCAGAGGTACTGGTTAAAA
TGCGTAACAGAATGAAAAAACGCGCTGAGCTATACGAAATGCTAACAGAAAGAGAAATGGAGATTTTATTGTTAATTGCT
AAAGGCTATTCCAATCAAGAGATCGCTAGTGCATCTCATATCACAATAAAAACAGTCAAAACACATGTAAGTAATATTCT
AAGTAAATTGGAAGTTCAAGATAGAACACAAGCAGTCATTTATGCTTTCCAACATAACTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.258

100

0.943
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368