Detailed information NTG0633040

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LRP64_RS09610
• Genome accession: NZ_CP088158
• Coordinates: 1966525..1967568 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 697
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1961525..1972568

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LRP64_RS09580 (LRP64_09580)	-	1961947..1963203 (-)	1257	WP_078065149.1	aminopeptidase	-
LRP64_RS09585 (LRP64_09585)	-	1963206..1963406 (-)	201	WP_000180460.1	DUF1128 family protein	-
LRP64_RS09590 (LRP64_09590)	-	1963553..1964017 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
LRP64_RS09595 (LRP64_09595)	-	1964024..1964299 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
LRP64_RS09600 (LRP64_09600)	-	1964577..1965821 (+)	1245	WP_064125696.1	YihY/virulence factor BrkB family protein	-
LRP64_RS09605 (LRP64_09605)	vraR	1965906..1966535 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
LRP64_RS09610 (LRP64_09610)	vraS	1966525..1967568 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LRP64_RS09615 (LRP64_09615)	liaF	1967565..1968266 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
LRP64_RS09620 (LRP64_09620)	-	1968281..1968667 (-)	387	WP_240696954.1	hypothetical protein	-
LRP64_RS09625 (LRP64_09625)	map	1968884..1969642 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
LRP64_RS09630 (LRP64_09630)	-	1970171..1971157 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
LRP64_RS09635 (LRP64_09635)	-	1971590..1972003 (-)	414	WP_025174552.1	hypothetical protein	-
LRP64_RS09640 (LRP64_09640)	-	1972032..1972142 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=633040 LRP64_RS09610 WP_001017131.1 1966525..1967568(-) (vraS) [Staphylococcus aureus strain 697]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=633040 LRP64_RS09610 WP_001017131.1 1966525..1967568(-) (vraS) [Staphylococcus aureus strain 697]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1