Detailed information NTG0632980

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: N7J25_RS01145
• Genome accession: NZ_CP104750
• Coordinates: 192149..192610 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874060.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain TAH 10/84 dMrvR
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 187149..197610

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N7J25_RS01115 (N7J25_01115)	-	188765..189130 (+)	366	WP_000285373.1	DUF1033 family protein	-
N7J25_RS01120 (N7J25_01120)	comGA	189302..190273 (+)	972	WP_000250801.1	competence type IV pilus ATPase ComGA	Machinery gene
N7J25_RS01125 (N7J25_01125)	comGB	190167..191210 (+)	1044	WP_228313184.1	competence type IV pilus assembly protein ComGB	Machinery gene
N7J25_RS01130 (N7J25_01130)	comGC/cglC	191207..191536 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
N7J25_RS01135 (N7J25_01135)	comGD	191511..191924 (+)	414	WP_000244259.1	competence type IV pilus minor pilin ComGD	Machinery gene
N7J25_RS01140 (N7J25_01140)	comGE	191896..192195 (+)	300	WP_038406052.1	competence type IV pilus minor pilin ComGE	Machinery gene
N7J25_RS01145 (N7J25_01145)	comGF	192149..192610 (+)	462	WP_001874060.1	competence type IV pilus minor pilin ComGF	Machinery gene
N7J25_RS01150 (N7J25_01150)	comGG	192588..192959 (+)	372	WP_000601105.1	competence type IV pilus minor pilin ComGG	Machinery gene
N7J25_RS01155 (N7J25_01155)	comGH	193074..194048 (+)	975	WP_001008567.1	class I SAM-dependent methyltransferase	Machinery gene
N7J25_RS01160 (N7J25_01160)	-	194080..195273 (+)	1194	WP_000047534.1	acetate kinase	-
N7J25_RS01165 (N7J25_01165)	-	195401..195593 (+)	193	Protein_173	helix-turn-helix transcriptional regulator	-
N7J25_RS01170 (N7J25_01170)	-	195572..195838 (+)	267	Protein_174	hypothetical protein	-
N7J25_RS01175 (N7J25_01175)	-	195907..196572 (+)	666	WP_000008107.1	CPBP family intramembrane glutamic endopeptidase	-
N7J25_RS01180 (N7J25_01180)	proC	196593..197363 (-)	771	WP_001876660.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17861.86 Da
• Isoelectric Point: 9.8392

>NTDB_id=632980 N7J25_RS01145 WP_001874060.1 192149..192610(+) (comGF) [Streptococcus agalactiae strain TAH 10/84 dMrvR]
MKVIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=632980 N7J25_RS01145 WP_001874060.1 192149..192610(+) (comGF) [Streptococcus agalactiae strain TAH 10/84 dMrvR]
TTGAAGGTAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTGCTAGTTTATCAAGGACTAACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTCGAAGGCGCTCACTTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTTCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAAACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373