Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LQF30_RS07810 Genome accession   NZ_CP088002
Coordinates   1608496..1609212 (+) Length   238 a.a.
NCBI ID   WP_001829999.1    Uniprot ID   C0LF82
Organism   Staphylococcus epidermidis strain IVK83     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1603496..1614212
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LQF30_RS07785 (LQF30_07770) - 1604896..1605681 (+) 786 WP_002494640.1 carbon-nitrogen family hydrolase -
  LQF30_RS07790 (LQF30_07775) hld 1606062..1606139 (-) 78 WP_002494082.1 delta-hemolysin -
  LQF30_RS07795 (LQF30_07780) - 1606456..1607019 (+) 564 WP_258500322.1 accessory gene regulator AgrB -
  LQF30_RS07800 (LQF30_07785) agrD 1607025..1607165 (+) 141 WP_002447513.1 cyclic lactone autoinducer peptide AgrD -
  LQF30_RS07805 (LQF30_07790) agrC 1607190..1608479 (+) 1290 WP_258500321.1 quorum-sensing sensor histidine kinase AgrC -
  LQF30_RS07810 (LQF30_07795) agrA 1608496..1609212 (+) 717 WP_001829999.1 quorum-sensing response regulator AgrA Regulator
  LQF30_RS07815 (LQF30_07800) - 1609280..1610239 (-) 960 WP_258500320.1 carbohydrate kinase -
  LQF30_RS07820 (LQF30_07805) - 1610246..1611718 (-) 1473 WP_002494642.1 sucrose-6-phosphate hydrolase -
  LQF30_RS07825 (LQF30_07810) - 1611978..1612931 (-) 954 WP_002494643.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.97 Da        Isoelectric Point: 5.6250

>NTDB_id=632272 LQF30_RS07810 WP_001829999.1 1608496..1609212(+) (agrA) [Staphylococcus epidermidis strain IVK83]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=632272 LQF30_RS07810 WP_001829999.1 1608496..1609212(+) (agrA) [Staphylococcus epidermidis strain IVK83]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAGCTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAAGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCAAAAGAAAGTAATGTAGATACGATTGAGTTAAAGCGGGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATTGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ACTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0LF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374