Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SAGCMC97051_RS05635 Genome accession   NZ_AP020310
Coordinates   1056263..1057576 (-) Length   437 a.a.
NCBI ID   WP_000042580.1    Uniprot ID   Q8DZW2
Organism   Streptococcus agalactiae strain GCMC97051     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1051263..1062576
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAGCMC97051_RS05615 (SAGCMC97051_10320) ffh 1051608..1053173 (-) 1566 WP_000863589.1 signal recognition particle protein -
  SAGCMC97051_RS05620 (SAGCMC97051_10330) - 1053191..1053523 (-) 333 WP_000402075.1 putative DNA-binding protein -
  SAGCMC97051_RS05625 (SAGCMC97051_10340) - 1053665..1054798 (-) 1134 WP_000564846.1 ISAs1-like element IS1548 family transposase -
  SAGCMC97051_RS05630 (SAGCMC97051_10350) - 1054991..1056124 (-) 1134 WP_000564846.1 ISAs1-like element IS1548 family transposase -
  SAGCMC97051_RS05635 (SAGCMC97051_10360) ciaH 1056263..1057576 (-) 1314 WP_000042580.1 sensor histidine kinase Regulator
  SAGCMC97051_RS05640 (SAGCMC97051_10370) ciaR 1057560..1058240 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  SAGCMC97051_RS05645 (SAGCMC97051_10380) - 1058402..1060951 (-) 2550 WP_000859382.1 M1 family metallopeptidase -
  SAGCMC97051_RS05650 (SAGCMC97051_10390) phoU 1061097..1061750 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  SAGCMC97051_RS05655 (SAGCMC97051_10400) pstB 1061784..1062542 (-) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49708.14 Da        Isoelectric Point: 9.4961

>NTDB_id=63224 SAGCMC97051_RS05635 WP_000042580.1 1056263..1057576(-) (ciaH) [Streptococcus agalactiae strain GCMC97051]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDIILFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRTPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLITQENGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=63224 SAGCMC97051_RS05635 WP_000042580.1 1056263..1057576(-) (ciaH) [Streptococcus agalactiae strain GCMC97051]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTATTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAACATCTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCCCTAGCTGTCTTACAAAATCGCCTAGAAACGCTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCACCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATCCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGGTTTGGCCTC
GGCCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DZW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.14

98.169

0.59
  ciaH Streptococcus pneumoniae Rx1

51.781

96.339

0.499
  ciaH Streptococcus pneumoniae D39

51.781

96.339

0.499
  ciaH Streptococcus pneumoniae R6

51.781

96.339

0.499
  ciaH Streptococcus pneumoniae TIGR4

51.781

96.339

0.499

Multiple sequence alignment