Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N5913_RS17945 Genome accession   NZ_CP104649
Coordinates   3446168..3446758 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain PNUSAE008512     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3441168..3451758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5913_RS17930 (N5913_17930) uhpT 3441970..3443361 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  N5913_RS17935 (N5913_17935) uhpC 3443499..3444818 (-) 1320 WP_001301991.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  N5913_RS17940 (N5913_17940) uhpB 3444828..3446168 (-) 1341 WP_261589762.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  N5913_RS17945 (N5913_17945) letA 3446168..3446758 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  N5913_RS17950 (N5913_17950) - 3446920..3448023 (-) 1104 WP_001089794.1 hypothetical protein -
  N5913_RS17955 (N5913_17955) - 3448631..3449113 (-) 483 WP_000229982.1 hypothetical protein -
  N5913_RS17960 (N5913_17960) - 3449359..3449916 (-) 558 WP_001462301.1 hypothetical protein -
  N5913_RS17965 (N5913_17965) ilvN 3450179..3450469 (-) 291 WP_001181706.1 acetolactate synthase small subunit -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=632216 N5913_RS17945 WP_000633668.1 3446168..3446758(-) (letA) [Escherichia coli strain PNUSAE008512]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=632216 N5913_RS17945 WP_000633668.1 3446168..3446758(-) (letA) [Escherichia coli strain PNUSAE008512]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGTGGCTTTCTCTCCAAGCGTTGTAGCCCTGACGA
ACTGATTGCTGCGGTGCATACGGTTGCCACAGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCACTAACCAAACGTGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378