Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N4555_RS26655 Genome accession   NZ_CP104639
Coordinates   5379297..5379953 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain PNUSAE014970     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5374297..5384953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N4555_RS26625 (N4555_26625) yecA 5375549..5376214 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  N4555_RS26645 (N4555_26645) pgsA 5376863..5377411 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N4555_RS26650 (N4555_26650) uvrC 5377468..5379300 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N4555_RS26655 (N4555_26655) letA 5379297..5379953 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N4555_RS27575 - 5380095..5380211 (+) 117 WP_001302039.1 hypothetical protein -
  N4555_RS26660 (N4555_26660) yecU 5380249..5380425 (+) 177 WP_001302050.1 protein YecU -
  N4555_RS26665 (N4555_26665) yecF 5380412..5380636 (+) 225 WP_000106479.1 DUF2594 family protein YecF -
  N4555_RS26670 (N4555_26670) sdiA 5380704..5381426 (-) 723 WP_001154288.1 transcriptional regulator SdiA -
  N4555_RS26675 (N4555_26675) tcyN 5381656..5382408 (-) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N4555_RS26680 (N4555_26680) tcyL 5382405..5383073 (-) 669 WP_001158226.1 cystine ABC transporter permease -
  N4555_RS26685 (N4555_26685) dcyD 5383088..5384074 (-) 987 WP_001128225.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=632011 N4555_RS26655 WP_000611328.1 5379297..5379953(-) (letA) [Escherichia coli strain PNUSAE014970]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=632011 N4555_RS26655 WP_000611328.1 5379297..5379953(-) (letA) [Escherichia coli strain PNUSAE014970]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482