Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N5855_RS18185 Genome accession   NZ_CP104629
Coordinates   3792558..3793148 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain AHM21C2872I     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3787558..3798148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5855_RS18170 (N5855_18130) uhpT 3788198..3789589 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  N5855_RS18175 (N5855_18135) uhpC 3789727..3791046 (-) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  N5855_RS18180 (N5855_18140) uhpB 3791056..3792558 (-) 1503 WP_001308147.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  N5855_RS18185 (N5855_18145) letA 3792558..3793148 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  N5855_RS18190 (N5855_18150) - 3793310..3794413 (-) 1104 WP_001308148.1 hypothetical protein -
  N5855_RS18195 (N5855_18155) - 3795021..3796322 (-) 1302 WP_000168044.1 hypothetical protein -
  N5855_RS18200 (N5855_18160) ilvN 3796585..3796875 (-) 291 WP_001181706.1 acetolactate synthase small subunit -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=631911 N5855_RS18185 WP_000633668.1 3792558..3793148(-) (letA) [Escherichia coli strain AHM21C2872I]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=631911 N5855_RS18185 WP_000633668.1 3792558..3793148(-) (letA) [Escherichia coli strain AHM21C2872I]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAGCCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGGGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTGACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378