Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   N5855_RS14800 Genome accession   NZ_CP104629
Coordinates   3089519..3090178 (+) Length   219 a.a.
NCBI ID   WP_001221486.1    Uniprot ID   -
Organism   Escherichia coli strain AHM21C2872I     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3084519..3095178
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5855_RS14785 (N5855_14745) ygiS 3086725..3088331 (-) 1607 Protein_2902 ABC transporter substrate-binding protein -
  N5855_RS14790 (N5855_14750) ygiV 3088440..3088922 (-) 483 WP_000183494.1 GyrI-like domain-containing protein -
  N5855_RS14795 (N5855_14755) ygiW 3088975..3089367 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  N5855_RS14800 (N5855_14760) ciaR 3089519..3090178 (+) 660 WP_001221486.1 quorum sensing response regulator transcription factor QseB Regulator
  N5855_RS14805 (N5855_14765) qseC 3090175..3091524 (+) 1350 WP_000673348.1 quorum sensing histidine kinase QseC -
  N5855_RS14810 (N5855_14770) ygiZ 3091570..3091902 (-) 333 WP_000912091.1 DUF2645 family protein -
  N5855_RS14815 (N5855_14775) mdaB 3092260..3092841 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  N5855_RS14820 (N5855_14780) ygiN 3092872..3093186 (+) 315 WP_000958598.1 putative quinol monooxygenase -
  N5855_RS14825 (N5855_14785) parE 3093234..3095126 (-) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24692.61 Da        Isoelectric Point: 6.3527

>NTDB_id=631898 N5855_RS14800 WP_001221486.1 3089519..3090178(+) (ciaR) [Escherichia coli strain AHM21C2872I]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGCQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=631898 N5855_RS14800 WP_001221486.1 3089519..3090178(+) (ciaR) [Escherichia coli strain AHM21C2872I]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTTGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365