Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N5861_RS22340 Genome accession   NZ_CP104598
Coordinates   4629762..4630352 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain AHM8C160RI     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4624762..4635352
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5861_RS22325 (N5861_22260) uhpT 4625284..4626675 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  N5861_RS22330 (N5861_22265) uhpC 4626931..4628250 (-) 1320 WP_001402648.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  N5861_RS22335 (N5861_22270) uhpB 4628260..4629762 (-) 1503 WP_085008071.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  N5861_RS22340 (N5861_22275) letA 4629762..4630352 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  N5861_RS22345 (N5861_22280) - 4630513..4631838 (-) 1326 WP_227466282.1 hypothetical protein -
  N5861_RS22350 (N5861_22285) - 4632226..4633194 (+) 969 WP_000654812.1 IS5-like element IS903B family transposase -
  N5861_RS22355 (N5861_22290) - 4633319..4634614 (-) 1296 WP_094318171.1 hypothetical protein -
  N5861_RS22360 (N5861_22295) ilvN 4634877..4635167 (-) 291 WP_001181706.1 acetolactate synthase small subunit -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=631678 N5861_RS22340 WP_000633668.1 4629762..4630352(-) (letA) [Escherichia coli strain AHM8C160RI]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=631678 N5861_RS22340 WP_000633668.1 4629762..4630352(-) (letA) [Escherichia coli strain AHM8C160RI]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGTGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCAGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTGATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGTTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTTGA
ACTGGCTCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378