Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N5B57_RS00180 Genome accession   NZ_CP104595
Coordinates   34424..35014 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain EC9952     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 29424..40014
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5B57_RS00150 (N5B57_00150) emrD 29906..31090 (-) 1185 WP_001349998.1 multidrug efflux MFS transporter EmrD -
  N5B57_RS00155 (N5B57_00155) ysdE 31172..31246 (+) 75 WP_211180519.1 protein YsdE -
  N5B57_RS00160 (N5B57_00160) tisB 31509..31598 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  N5B57_RS00165 (N5B57_00165) ivbL 32163..32261 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  N5B57_RS00170 (N5B57_00170) ilvB 32367..34055 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  N5B57_RS00175 (N5B57_00175) ilvN 34059..34349 (+) 291 WP_001181713.1 acetolactate synthase small subunit -
  N5B57_RS00180 (N5B57_00180) letA 34424..35014 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  N5B57_RS00185 (N5B57_00185) uhpB 35014..36516 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  N5B57_RS00190 (N5B57_00190) uhpC 36526..37845 (+) 1320 WP_001296914.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  N5B57_RS00195 (N5B57_00195) uhpT 37983..39374 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=631525 N5B57_RS00180 WP_000633668.1 34424..35014(+) (letA) [Escherichia coli strain EC9952]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=631525 N5B57_RS00180 WP_000633668.1 34424..35014(+) (letA) [Escherichia coli strain EC9952]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378