Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N5O79_RS16220 Genome accession   NZ_CP104516
Coordinates   3227597..3228187 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain E4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3222597..3233187
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5O79_RS16185 (N5O79_16185) yidF 3222713..3223210 (+) 498 WP_000148063.1 radical SAM protein -
  N5O79_RS16190 (N5O79_16190) emrD 3223218..3224402 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  N5O79_RS16195 (N5O79_16195) ysdE 3224484..3224558 (+) 75 WP_211180519.1 protein YsdE -
  N5O79_RS16200 (N5O79_16200) tisB 3224682..3224771 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  N5O79_RS16205 (N5O79_16205) ivbL 3225336..3225434 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  N5O79_RS16210 (N5O79_16210) ilvB 3225540..3227228 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  N5O79_RS16215 (N5O79_16215) ilvN 3227232..3227522 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  N5O79_RS16220 (N5O79_16220) letA 3227597..3228187 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  N5O79_RS16225 (N5O79_16225) uhpB 3228187..3229689 (+) 1503 WP_053295569.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  N5O79_RS16230 (N5O79_16230) uhpC 3229699..3231018 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  N5O79_RS16235 (N5O79_16235) uhpT 3231156..3232547 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=630187 N5O79_RS16220 WP_000633668.1 3227597..3228187(+) (letA) [Escherichia coli strain E4]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=630187 N5O79_RS16220 WP_000633668.1 3227597..3228187(+) (letA) [Escherichia coli strain E4]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGTCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378