Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N5O81_RS14815 Genome accession   NZ_CP104503
Coordinates   3054215..3054805 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain E1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3049215..3059805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5O81_RS14800 (N5O81_14800) uhpT 3049855..3051246 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  N5O81_RS14805 (N5O81_14805) uhpC 3051384..3052703 (-) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  N5O81_RS14810 (N5O81_14810) uhpB 3052713..3054215 (-) 1503 WP_001314238.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  N5O81_RS14815 (N5O81_14815) letA 3054215..3054805 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  N5O81_RS14820 (N5O81_14820) - 3055220..3056080 (+) 861 WP_001259006.1 DUF6708 domain-containing protein -
  N5O81_RS14825 (N5O81_14825) ilvN 3056271..3056561 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  N5O81_RS14830 (N5O81_14830) ilvB 3056565..3058253 (-) 1689 WP_000168476.1 acetolactate synthase large subunit -
  N5O81_RS14835 (N5O81_14835) ivbL 3058359..3058457 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  N5O81_RS14840 (N5O81_14840) ysdE 3058702..3058776 (-) 75 WP_211180519.1 protein YsdE -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=630017 N5O81_RS14815 WP_000633668.1 3054215..3054805(-) (letA) [Escherichia coli strain E1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=630017 N5O81_RS14815 WP_000633668.1 3054215..3054805(-) (letA) [Escherichia coli strain E1]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACATGTCCATCGCGCCAACCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378