Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N1H43_RS22520 Genome accession   NZ_CP104442
Coordinates   4625832..4626422 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain HBUT-L     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4620832..4631422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N1H43_RS22505 (N1H43_22510) uhpT 4621472..4622863 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  N1H43_RS22510 (N1H43_22515) uhpC 4623001..4624320 (-) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  N1H43_RS22515 (N1H43_22520) uhpB 4624330..4625832 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  N1H43_RS22520 (N1H43_22525) letA 4625832..4626422 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  N1H43_RS22525 (N1H43_22530) ilvN 4626497..4626787 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  N1H43_RS22530 (N1H43_22535) ilvB 4626791..4628479 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  N1H43_RS22535 (N1H43_22540) ivbL 4628585..4628683 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  N1H43_RS22540 (N1H43_22545) tisB 4629248..4629337 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  N1H43_RS22545 (N1H43_22550) ysdE 4629600..4629674 (-) 75 WP_211180519.1 protein YsdE -
  N1H43_RS22550 (N1H43_22555) emrD 4629756..4630940 (+) 1185 WP_001349998.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=629440 N1H43_RS22520 WP_000633668.1 4625832..4626422(-) (letA) [Escherichia coli strain HBUT-L]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=629440 N1H43_RS22520 WP_000633668.1 4625832..4626422(-) (letA) [Escherichia coli strain HBUT-L]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCTCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378