Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   N597_RS03020 Genome accession   NC_022582
Coordinates   591613..592986 (+) Length   457 a.a.
NCBI ID   WP_023022849.1    Uniprot ID   -
Organism   Streptococcus ilei     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 586613..597986
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N597_RS03000 (N597_03105) - 586897..589440 (+) 2544 WP_023022842.1 M1 family metallopeptidase -
  N597_RS03005 (N597_03110) - 589497..590039 (-) 543 WP_042361035.1 biotin transporter BioY -
  N597_RS03010 (N597_03115) - 590245..590835 (+) 591 WP_023022846.1 hypothetical protein -
  N597_RS03015 (N597_03120) ciaR 590949..591623 (+) 675 WP_023022847.1 response regulator transcription factor Regulator
  N597_RS03020 (N597_03125) ciaH 591613..592986 (+) 1374 WP_023022849.1 cell wall metabolism sensor histidine kinase WalK Regulator
  N597_RS03025 (N597_03130) - 593352..593738 (+) 387 WP_023022851.1 VOC family protein -
  N597_RS03030 (N597_03135) - 593933..595318 (+) 1386 WP_023022853.1 polysaccharide deacetylase family protein -
  N597_RS03035 (N597_03140) - 595500..596588 (-) 1089 WP_023022855.1 DEAD/DEAH box helicase -
  N597_RS03040 (N597_03145) - 596590..597567 (-) 978 WP_023022857.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 52509.81 Da        Isoelectric Point: 6.5330

>NTDB_id=62909 N597_RS03020 WP_023022849.1 591613..592986(+) (ciaH) [Streptococcus ilei]
MLNKIKKTVNADDFSYFIRYFGLFTLIFSTMTLIIIQVMRSSLYTTVDENLKILSKDRYSIISLANRTGNGMGRDEPDDD
RPEDNEPDPEDGPRPSVTSNSTAILLNDNFENVTTDNGFLDLKTVTFSRSYLNKIKQIQITNHYKQKESYRAYLVDIDPD
DYIDGVKYAVIMTNISQLEQTSEKHESQIALVMICFWGISLFASIFLAKMSVKPLLESMNRQKAFVENASHELRTPLAVL
QNRLETLFRKPEATIMESSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPEFCEIPPSFFDQTFANYEIIAEENDKIFE
YENHVERSLVSDKVLLKQLMTILYDNALKYTEEEGKIRFVAQFKDRYLYLRVEDNGPGIADEDKKRIFDRFYRVDKARTR
QKGGFGLGLSLAKQIVEAFNGTITVRDNKPKGAIFEVKLATKSDSKKKSTSKSTKNK

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=62909 N597_RS03020 WP_023022849.1 591613..592986(+) (ciaH) [Streptococcus ilei]
ATGCTCAATAAAATTAAAAAAACTGTCAATGCGGATGACTTTTCTTATTTCATCCGCTATTTCGGACTCTTTACCTTGAT
TTTCTCAACCATGACCTTGATTATTATTCAAGTAATGCGGTCAAGTCTGTATACAACGGTTGATGAAAATTTAAAGATAC
TGAGTAAAGATCGTTATTCCATCATTAGCTTGGCCAATCGTACCGGAAATGGGATGGGAAGAGACGAACCAGATGATGAC
CGACCAGAAGATAATGAACCTGATCCCGAGGATGGCCCTAGACCATCGGTCACTTCCAATAGTACAGCCATCCTCTTGAA
TGATAATTTTGAAAATGTGACGACGGACAATGGTTTTCTGGATTTAAAAACAGTGACCTTTAGTCGCAGCTATTTAAACA
AGATCAAGCAGATTCAAATCACCAACCATTATAAGCAAAAAGAAAGCTACCGGGCTTATTTGGTGGATATTGACCCCGAT
GATTATATCGATGGGGTGAAATATGCCGTGATCATGACCAATATCAGCCAGTTGGAGCAGACCAGTGAAAAACACGAGAG
CCAAATCGCCTTGGTCATGATTTGCTTCTGGGGCATTTCCCTCTTTGCAAGTATCTTCCTGGCTAAAATGAGTGTGAAAC
CTCTCTTAGAGAGCATGAATCGGCAAAAGGCCTTTGTCGAAAATGCTTCTCATGAATTGCGGACACCTTTAGCCGTTTTG
CAAAATCGTTTGGAAACCCTGTTCCGAAAGCCAGAGGCAACAATTATGGAATCCAGTGAGAATATCGCCTCCTCTTTGGA
TGAGGTTCGCAATATGCGCTTACTGACGACCAATCTCTTAAACTTAGCCCGTCGAGATGATGGGATTAAACCTGAGTTTT
GTGAAATCCCTCCTTCTTTTTTCGACCAAACCTTTGCCAATTATGAAATCATTGCCGAGGAAAATGATAAAATCTTCGAG
TATGAGAATCATGTCGAAAGGAGTCTGGTGTCTGACAAGGTCCTACTGAAACAGCTGATGACCATTTTGTATGACAATGC
CCTCAAATATACGGAGGAAGAAGGAAAGATACGGTTTGTCGCCCAATTCAAGGATCGCTATCTCTATCTTCGGGTAGAGG
ATAATGGACCAGGGATTGCAGACGAAGATAAAAAGCGGATATTTGATCGATTCTACCGAGTGGATAAGGCGCGTACGCGT
CAAAAGGGTGGTTTTGGTTTAGGACTGTCCTTAGCCAAGCAAATCGTAGAAGCCTTTAATGGCACCATTACTGTTCGAGA
TAACAAGCCGAAAGGTGCTATTTTCGAGGTCAAACTAGCAACCAAGTCAGATAGTAAAAAGAAATCAACTTCTAAATCAA
CGAAAAACAAGTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(223-288)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(332-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae D39

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae R6

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae TIGR4

60.356

98.249

0.593
  ciaH Streptococcus mutans UA159

50.342

96.061

0.484

Multiple sequence alignment