Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N1705_RS00410 Genome accession   NZ_CP104123
Coordinates   81806..82396 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain USDA-ARS-USMARC-49610     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 76806..87396
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N1705_RS00380 (N1705_00380) emrD 77288..78472 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  N1705_RS00385 (N1705_00385) ysdE 78554..78628 (+) 75 WP_211180519.1 protein YsdE -
  N1705_RS00390 (N1705_00390) tisB 78890..78979 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  N1705_RS00395 (N1705_00395) ivbL 79545..79643 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  N1705_RS00400 (N1705_00400) ilvB 79749..81437 (+) 1689 WP_219411787.1 acetolactate synthase large subunit -
  N1705_RS00405 (N1705_00405) ilvN 81441..81731 (+) 291 WP_001181713.1 acetolactate synthase small subunit -
  N1705_RS00410 (N1705_00410) letA 81806..82396 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  N1705_RS00415 (N1705_00415) uhpB 82396..83898 (+) 1503 WP_096835494.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  N1705_RS00420 (N1705_00420) uhpC 83908..85227 (+) 1320 WP_000936560.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  N1705_RS00425 (N1705_00425) uhpT 85483..86874 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=627302 N1705_RS00410 WP_000633668.1 81806..82396(+) (letA) [Escherichia coli strain USDA-ARS-USMARC-49610]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=627302 N1705_RS00410 WP_000633668.1 81806..82396(+) (letA) [Escherichia coli strain USDA-ARS-USMARC-49610]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378