Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N1709_RS10200 Genome accession   NZ_CP104117
Coordinates   2076765..2077421 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain USDA-ARS-USMARC-50748     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2071765..2082421
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N1709_RS10170 (N1709_10170) dcyD 2072645..2073631 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  N1709_RS10175 (N1709_10175) tcyL 2073646..2074314 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  N1709_RS10180 (N1709_10180) tcyN 2074311..2075063 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N1709_RS10185 (N1709_10185) sdiA 2075293..2076015 (+) 723 WP_001154266.1 transcriptional regulator SdiA -
  N1709_RS10190 (N1709_10190) yecF 2076082..2076306 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  N1709_RS10195 (N1709_10195) yecU 2076293..2076469 (-) 177 WP_001307856.1 protein YecU -
  N1709_RS25455 - 2076552..2076623 (-) 72 Protein_1998 transcriptional regulator -
  N1709_RS10200 (N1709_10200) letA 2076765..2077421 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N1709_RS10205 (N1709_10205) uvrC 2077418..2079250 (+) 1833 WP_001283426.1 excinuclease ABC subunit UvrC Machinery gene
  N1709_RS10210 (N1709_10210) pgsA 2079307..2079855 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N1709_RS10230 (N1709_10230) yecA 2080504..2081169 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=627259 N1709_RS10200 WP_000611328.1 2076765..2077421(+) (letA) [Escherichia coli strain USDA-ARS-USMARC-50748]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=627259 N1709_RS10200 WP_000611328.1 2076765..2077421(+) (letA) [Escherichia coli strain USDA-ARS-USMARC-50748]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482