Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N1706_RS13480 Genome accession   NZ_CP104114
Coordinates   2774269..2774925 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain USDA-ARS-USMARC-51408     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2769269..2779925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N1706_RS13450 (N1706_13450) yecA 2770520..2771185 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  N1706_RS13470 (N1706_13470) pgsA 2771835..2772383 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N1706_RS13475 (N1706_13475) uvrC 2772440..2774272 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N1706_RS13480 (N1706_13480) letA 2774269..2774925 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N1706_RS24465 - 2775067..2775138 (+) 72 Protein_2630 transcriptional regulator -
  N1706_RS13485 (N1706_13485) yecU 2775221..2775397 (+) 177 WP_032231304.1 protein YecU -
  N1706_RS13490 (N1706_13490) yecF 2775384..2775608 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  N1706_RS13495 (N1706_13495) sdiA 2775675..2776397 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  N1706_RS13500 (N1706_13500) tcyN 2776627..2777379 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N1706_RS13505 (N1706_13505) tcyL 2777376..2778044 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  N1706_RS13510 (N1706_13510) dcyD 2778059..2779045 (-) 987 WP_001128222.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=627182 N1706_RS13480 WP_000611335.1 2774269..2774925(-) (letA) [Escherichia coli strain USDA-ARS-USMARC-51408]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=627182 N1706_RS13480 WP_000611335.1 2774269..2774925(-) (letA) [Escherichia coli strain USDA-ARS-USMARC-51408]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCAGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486