Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NZ657_RS10140 Genome accession   NZ_CP103974
Coordinates   2104089..2104745 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain DLI.6n     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2099089..2109745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NZ657_RS10110 (NZ657_10110) dcyD 2099969..2100955 (+) 987 WP_001128222.1 D-cysteine desulfhydrase -
  NZ657_RS10115 (NZ657_10115) tcyL 2100970..2101638 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NZ657_RS10120 (NZ657_10120) tcyN 2101635..2102387 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NZ657_RS10125 (NZ657_10125) sdiA 2102617..2103339 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  NZ657_RS10130 (NZ657_10130) yecF 2103406..2103630 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NZ657_RS10135 (NZ657_10135) yecU 2103617..2103793 (-) 177 WP_001326718.1 protein YecU -
  NZ657_RS24985 - 2103876..2103947 (-) 72 Protein_1995 transcriptional regulator -
  NZ657_RS10140 (NZ657_10140) letA 2104089..2104745 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NZ657_RS10145 (NZ657_10145) uvrC 2104742..2106574 (+) 1833 WP_001283429.1 excinuclease ABC subunit UvrC Machinery gene
  NZ657_RS10150 (NZ657_10150) pgsA 2106631..2107179 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NZ657_RS10170 (NZ657_10170) yecA 2107829..2108494 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=626133 NZ657_RS10140 WP_000611335.1 2104089..2104745(+) (letA) [Escherichia coli strain DLI.6n]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=626133 NZ657_RS10140 WP_000611335.1 2104089..2104745(+) (letA) [Escherichia coli strain DLI.6n]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486