Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LK336_RS00425 Genome accession   NZ_CP086572
Coordinates   80135..80764 (+) Length   209 a.a.
NCBI ID   WP_000153529.1    Uniprot ID   A0A7U7PW36
Organism   Staphylococcus argenteus strain RIVM_M036020     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 75135..85764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK336_RS00400 (LK336_00400) - 75507..76493 (-) 987 WP_031788370.1 aromatic acid exporter family protein -
  LK336_RS00405 (LK336_00405) map 77024..77782 (+) 759 WP_031788218.1 type I methionyl aminopeptidase -
  LK336_RS00410 (LK336_00410) - 78003..78389 (+) 387 WP_001110170.1 hypothetical protein -
  LK336_RS00415 (LK336_00415) liaF 78404..79105 (+) 702 WP_031788217.1 cell wall-active antibiotics response protein LiaF -
  LK336_RS00420 (LK336_00420) vraS 79102..80145 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  LK336_RS00425 (LK336_00425) vraR 80135..80764 (+) 630 WP_000153529.1 two-component system response regulator VraR Regulator
  LK336_RS00430 (LK336_00430) - 80880..82103 (-) 1224 WP_000037065.1 YihY/virulence factor BrkB family protein -
  LK336_RS00435 (LK336_00435) - 82382..82657 (-) 276 WP_000428174.1 YtxH domain-containing protein -
  LK336_RS00440 (LK336_00440) - 82664..83128 (-) 465 WP_000228669.1 low molecular weight protein-tyrosine-phosphatase -
  LK336_RS00445 (LK336_00445) - 83275..83475 (+) 201 WP_000180459.1 DUF1128 family protein -
  LK336_RS00450 (LK336_00450) - 83487..84734 (+) 1248 WP_000656301.1 aminopeptidase -
  LK336_RS00455 (LK336_00455) - 84826..85356 (+) 531 WP_000184380.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23517.28 Da        Isoelectric Point: 5.3889

>NTDB_id=625517 LK336_RS00425 WP_000153529.1 80135..80764(+) (vraR) [Staphylococcus argenteus strain RIVM_M036020]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSKGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=625517 LK336_RS00425 WP_000153529.1 80135..80764(+) (vraR) [Staphylococcus argenteus strain RIVM_M036020]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTAGGTGAGGGGGCTTCAGGTAAAGAAGCAATCGCTAAAGCCCATGAGCTAAAACCTGATTTGATTTTAA
TGGATTTGCTTATGGATGATATGGATGGTGTAGAAGCGACTACTCAAATTAAAAAAGATTTACCACAAATTAAAGTATTA
ATGCTAACAAGTTTTATTGAAGATAAAGAGGTATATCGTGCCTTAGATGCAGGTGTTGATAGCTATATTTTAAAAACAAC
GAGTGCAAAAGATATTGCTGATGCAGTTCGTAAAACATCTAAAGGTGAATCTGTATTTGAACCTGAAGTATTAGTAAAAA
TGCGTAACCGTATGAAAAAACGTGCTGAGTTATATGAAATGTTAACGGAACGTGAAATGGAAATATTATTATTAATTGCC
AAAGGTTATTCAAATCAAGAGATTGCAAGTGCATCTCATATTACAATTAAAACAGTTAAGACACATGTAAGTAATATTTT
AAGTAAGTTAGAAGTACAAGATAGAACACAAGCCGTTATTTATGCATTCCAACATAATTTAATTCAGTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7PW36

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.043

100

0.99
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373