Detailed information NTG0062524

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: N288_RS20520
• Genome accession: NC_022524
• Coordinates: 4060802..4061944 (-)
• Length: 380 a.a.
• NCBI ID: WP_009792966.1
• Uniprot ID: U5LEJ8
• Organism: Bacillus infantis NRRL B-14911
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4055802..4066944

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N288_RS20500 (N288_22095)	-	4056178..4057107 (+)	930	WP_009792972.1	manganese-dependent inorganic pyrophosphatase	-
N288_RS20505 (N288_22100)	-	4057146..4057985 (-)	840	WP_009792971.1	DegV family protein	-
N288_RS24920 (N288_22105)	-	4058126..4058278 (-)	153	WP_009792970.1	sporulation histidine kinase inhibitor Sda	-
N288_RS20510 (N288_22110)	-	4058631..4059770 (+)	1140	WP_022544409.1	IS110 family transposase	-
N288_RS20515 (N288_22115)	degU	4059944..4060627 (-)	684	WP_009792967.1	response regulator	Regulator
N288_RS20520 (N288_22120)	degS	4060802..4061944 (-)	1143	WP_009792966.1	sensor histidine kinase	Regulator
N288_RS20525 (N288_22125)	-	4062357..4062992 (+)	636	WP_009792965.1	YigZ family protein	-
N288_RS20530 (N288_22130)	-	4063079..4064125 (+)	1047	WP_035402016.1	LCP family protein	-
N288_RS20535 (N288_22135)	-	4064490..4065368 (+)	879	WP_009792963.1	helix-turn-helix domain-containing protein	-
N288_RS20540 (N288_22140)	-	4065521..4066183 (+)	663	WP_009792962.1	hypothetical protein	-

Sequence

Protein

• Length: 380 a.a.
• Molecular weight: 44326.09 Da
• Isoelectric Point: 7.0737

>NTDB_id=62524 N288_RS20520 WP_009792966.1 4060802..4061944(-) (degS) [Bacillus infantis NRRL B-14911]
MTRKKFDTKTLDLILEKMVSTVGNSKDEIFRISEQCRQDFESLTSDLKEVKQAVVLTIDEGDQLEAQTRFARKRLSEVSM
HFKDYTESQVREAYEKAHQLQMKLSMNRQQEKQLRERRDDIERRLLGIQETIDRAEHLVSQISVVMNYLMSDLKRMGEVL
EDAKLKQDFGLKIIEAQEEERKRLSREIHDGPAQMMANVMMRSDLIERIYKERGAGEAITEIKSLKKMVRNALYEVRRII
YDLRPMALDDLGLVPTLRKYLQTIEEYHNTVKIYFSNVGDEKRLPPKYEVALFRLVQESVQNALKHAEAKEIKVKLEIRN
DSISVVIRDDGKGFDTSQKKPESFGMIGMRERVELLEGQISFDSKINAGTIVLIQVPFME

Nucleotide

• Length: 1143 bp

>NTDB_id=62524 N288_RS20520 WP_009792966.1 4060802..4061944(-) (degS) [Bacillus infantis NRRL B-14911]
ATGACTAGAAAAAAATTCGATACGAAGACACTCGATCTTATATTAGAAAAGATGGTATCCACTGTTGGAAACAGCAAGGA
TGAAATCTTCCGCATAAGCGAGCAATGCCGGCAGGACTTTGAAAGCTTGACAAGTGATTTGAAGGAAGTCAAACAGGCAG
TTGTCCTGACCATTGATGAGGGAGACCAGCTGGAAGCACAAACGAGGTTTGCCAGAAAAAGGCTTTCTGAAGTAAGCATG
CATTTCAAGGACTACACAGAAAGCCAGGTAAGAGAAGCGTATGAAAAGGCGCACCAGCTGCAGATGAAGCTTTCGATGAA
CCGCCAGCAGGAAAAGCAGCTTCGCGAACGGCGGGATGACATAGAACGAAGGCTGCTCGGCATCCAGGAAACCATTGACC
GCGCAGAACATCTCGTTTCCCAGATCTCGGTCGTCATGAACTATTTGATGAGCGACCTGAAGAGGATGGGAGAGGTCCTG
GAAGATGCAAAGCTTAAGCAGGATTTCGGCCTTAAGATCATTGAAGCGCAGGAGGAAGAGCGAAAAAGGCTGTCGAGGGA
AATTCATGACGGTCCTGCCCAGATGATGGCCAATGTGATGATGCGCTCTGACCTGATAGAAAGAATCTATAAGGAGCGGG
GAGCAGGCGAAGCCATCACTGAAATCAAAAGCCTTAAGAAGATGGTCAGAAATGCGCTTTACGAGGTCAGGAGGATTATC
TATGATCTTAGGCCTATGGCTCTCGATGACCTTGGACTGGTGCCGACTTTAAGGAAATATCTCCAAACCATTGAAGAATA
CCATAATACGGTGAAAATTTATTTCAGCAATGTCGGCGATGAAAAGCGGCTTCCGCCAAAATATGAGGTAGCTTTGTTCC
GGCTTGTCCAGGAATCTGTACAGAATGCTCTAAAGCATGCTGAGGCAAAAGAGATCAAAGTGAAGCTCGAAATCCGCAAT
GATTCTATTTCAGTTGTCATCAGGGATGACGGCAAAGGGTTTGACACGAGCCAGAAGAAGCCCGAATCCTTTGGGATGAT
CGGCATGAGGGAAAGAGTCGAACTGCTGGAAGGGCAGATATCCTTCGACTCCAAAATCAATGCCGGGACAATCGTGCTGA
TTCAGGTTCCTTTCATGGAATGA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (289-378)

• Histidine kinase (HisKA_3) (180-248)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: U5LEJ8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	62.663	100	0.632