Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M5T33_RS14285 Genome accession   NZ_CP103739
Coordinates   2879995..2880651 (-) Length   218 a.a.
NCBI ID   WP_000611338.1    Uniprot ID   -
Organism   Escherichia coli strain 3359     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2874995..2885651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5T33_RS14255 (M5T33_14255) yecA 2876246..2876911 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  M5T33_RS14275 (M5T33_14275) pgsA 2877561..2878109 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M5T33_RS14280 (M5T33_14280) uvrC 2878166..2879998 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M5T33_RS14285 (M5T33_14285) letA 2879995..2880651 (-) 657 WP_000611338.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M5T33_RS25735 - 2880793..2880909 (+) 117 WP_001302039.1 hypothetical protein -
  M5T33_RS14290 (M5T33_14290) yecU 2880947..2881123 (+) 177 WP_001302050.1 protein YecU -
  M5T33_RS14295 (M5T33_14295) yecF 2881110..2881334 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  M5T33_RS14300 (M5T33_14300) sdiA 2881402..2882124 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  M5T33_RS14305 (M5T33_14305) tcyN 2882354..2883106 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M5T33_RS14310 (M5T33_14310) tcyL 2883103..2883771 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  M5T33_RS14315 (M5T33_14315) dcyD 2883786..2884772 (-) 987 WP_001128219.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23908.65 Da        Isoelectric Point: 6.9614

>NTDB_id=624630 M5T33_RS14285 WP_000611338.1 2879995..2880651(-) (letA) [Escherichia coli strain 3359]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNSVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=624630 M5T33_RS14285 WP_000611338.1 2879995..2880651(-) (letA) [Escherichia coli strain 3359]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGCGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATTCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGCAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGTGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAGCAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.691

94.954

0.491
  letA Legionella pneumophila strain ERS1305867

51.691

94.954

0.491