Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M5S83_RS00280 Genome accession   NZ_CP103609
Coordinates   47550..48140 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 4314     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 42550..53140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5S83_RS00265 (M5S83_00265) uhpT 43072..44463 (-) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -
  M5S83_RS00270 (M5S83_00270) uhpC 44719..46038 (-) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  M5S83_RS00275 (M5S83_00275) uhpB 46048..47550 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  M5S83_RS00280 (M5S83_00280) letA 47550..48140 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  M5S83_RS00285 (M5S83_00285) ilvN 48215..48505 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  M5S83_RS00290 (M5S83_00290) ilvB 48509..50197 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  M5S83_RS00295 (M5S83_00295) ivbL 50303..50401 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  M5S83_RS00300 (M5S83_00300) tisB 50965..51054 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  M5S83_RS00305 (M5S83_00305) ysdE 51317..51391 (-) 75 WP_211180519.1 protein YsdE -
  M5S83_RS00310 (M5S83_00310) emrD 51473..52657 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=623600 M5S83_RS00280 WP_000633668.1 47550..48140(-) (letA) [Escherichia coli strain 4314]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=623600 M5S83_RS00280 WP_000633668.1 47550..48140(-) (letA) [Escherichia coli strain 4314]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378