Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M5S50_RS00180 Genome accession   NZ_CP103468
Coordinates   36219..36809 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 4973     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 31219..41809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5S50_RS00165 (M5S50_00165) ilvN 32504..32794 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  M5S50_RS00170 (M5S50_00170) - 33858..34340 (+) 483 WP_059337323.1 hypothetical protein -
  M5S50_RS00175 (M5S50_00175) - 34619..36057 (+) 1439 Protein_34 hypothetical protein -
  M5S50_RS00180 (M5S50_00180) letA 36219..36809 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  M5S50_RS00185 (M5S50_00185) uhpB 36809..38311 (+) 1503 WP_022646294.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  M5S50_RS00190 (M5S50_00190) uhpC 38321..39640 (+) 1320 WP_001301991.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  M5S50_RS00195 (M5S50_00195) uhpT 39778..41169 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=622268 M5S50_RS00180 WP_000633668.1 36219..36809(+) (letA) [Escherichia coli strain 4973]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=622268 M5S50_RS00180 WP_000633668.1 36219..36809(+) (letA) [Escherichia coli strain 4973]
ATGATCACCGTTGCACTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGTTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAGCGTTGTAGCCCTGACGA
ACTGATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTGACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCTAACCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378