Detailed information NTG0622173

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: NX050_RS21465
• Genome accession: NZ_CP103456
• Coordinates: 4012391..4013473 (-)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain PN176 (HK176)
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4007391..4018473

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NX050_RS21440 (NX050_21440)	cysE	4007496..4008149 (-)	654	WP_014478618.1	serine O-acetyltransferase	-
NX050_RS21445 (NX050_21445)	gltX	4008451..4009902 (-)	1452	WP_014478617.1	glutamate--tRNA ligase	-
NX050_RS21450 (NX050_21450)	ispF	4009993..4010469 (-)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
NX050_RS21455 (NX050_21455)	ispD	4010462..4011160 (-)	699	WP_014478616.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
NX050_RS21460 (NX050_21460)	yacL	4011175..4012275 (-)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
NX050_RS21465 (NX050_21465)	disA	4012391..4013473 (-)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
NX050_RS21470 (NX050_21470)	radA/sms	4013477..4014853 (-)	1377	WP_014475593.1	DNA repair protein RadA	Machinery gene
NX050_RS21475 (NX050_21475)	clpC	4014945..4017377 (-)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
NX050_RS21480 (NX050_21480)	mcsB	4017374..4018465 (-)	1092	WP_003235007.1	protein arginine kinase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=622173 NX050_RS21465 WP_003225736.1 4012391..4013473(-) (disA) [Bacillus subtilis strain PN176 (HK176)]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=622173 NX050_RS21465 WP_003225736.1 4012391..4013473(-) (disA) [Bacillus subtilis strain PN176 (HK176)]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTCCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1