Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   HIFGL_RS02915 Genome accession   NC_022356
Coordinates   586406..587080 (+) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae KR494     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 581406..592080
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIFGL_RS02880 (HifGL_000576) rpmG 582324..582494 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  HIFGL_RS02885 (HifGL_000577) rpmB 582506..582742 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  HIFGL_RS02890 (HifGL_000578) radC 582955..583620 (-) 666 WP_013526173.1 RadC family protein -
  HIFGL_RS02895 (HifGL_000579) coaBC 583783..584985 (+) 1203 WP_011272308.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  HIFGL_RS02900 (HifGL_000580) dut 585033..585488 (+) 456 WP_005631431.1 dUTP diphosphatase -
  HIFGL_RS02905 (HifGL_000581) slmA 585492..586148 (+) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  HIFGL_RS02910 (HifGL_000582) - 586170..586421 (+) 252 WP_005647999.1 YheU family protein -
  HIFGL_RS02915 (HifGL_000583) crp 586406..587080 (+) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  HIFGL_RS02920 (HifGL_000584) rlmC 587445..588620 (-) 1176 WP_021034785.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  HIFGL_RS02925 (HifGL_000585) nagZ 588613..589668 (-) 1056 WP_021034786.1 beta-N-acetylhexosaminidase -
  HIFGL_RS02930 (HifGL_000586) - 589672..590022 (-) 351 WP_005647993.1 YcfL family protein -
  HIFGL_RS02935 (HifGL_000587) hinT 590022..590372 (-) 351 WP_005627389.1 purine nucleoside phosphoramidase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=62167 HIFGL_RS02915 WP_005647998.1 586406..587080(+) (crp) [Haemophilus influenzae KR494]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=62167 HIFGL_RS02915 WP_005647998.1 586406..587080(+) (crp) [Haemophilus influenzae KR494]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGA
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment