Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   LK450_RS04810 Genome accession   NZ_CP085939
Coordinates   993496..994551 (-) Length   351 a.a.
NCBI ID   WP_003032358.1    Uniprot ID   A0A3S4NJ72
Organism   Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 988496..999551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK450_RS04775 (LK450_04775) - 988944..989324 (-) 381 WP_018543647.1 rhodanese-like domain-containing protein -
  LK450_RS04780 (LK450_04780) - 989318..989542 (-) 225 WP_003025724.1 YqgQ family protein -
  LK450_RS04785 (LK450_04785) - 989816..990343 (-) 528 WP_003032411.1 Dps family protein -
  LK450_RS04790 (LK450_04790) cclA/cilC 990497..991171 (+) 675 WP_018543646.1 A24 family peptidase Machinery gene
  LK450_RS04795 (LK450_04795) - 991166..991684 (-) 519 WP_003032357.1 VanZ family protein -
  LK450_RS04800 (LK450_04800) rlmN 991677..992759 (-) 1083 WP_018543645.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  LK450_RS04805 (LK450_04805) - 992793..993356 (-) 564 WP_026248195.1 YutD family protein -
  LK450_RS04810 (LK450_04810) sepM 993496..994551 (-) 1056 WP_003032358.1 SepM family pheromone-processing serine protease Regulator
  LK450_RS04815 (LK450_04815) coaD 994532..995029 (-) 498 WP_003032432.1 pantetheine-phosphate adenylyltransferase -
  LK450_RS04820 (LK450_04820) rsmD 995019..995567 (-) 549 WP_025271932.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  LK450_RS04825 (LK450_04825) hpf 995755..996297 (-) 543 WP_003032381.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  LK450_RS04830 (LK450_04830) comFC/cflB 996375..997040 (-) 666 WP_003032902.1 ComF family protein Machinery gene
  LK450_RS04835 (LK450_04835) comFA/cflA 997037..998338 (-) 1302 WP_022524394.1 DEAD/DEAH box helicase Machinery gene
  LK450_RS04840 (LK450_04840) - 998395..999030 (+) 636 WP_003032900.1 YigZ family protein -

Sequence

Protein


Download         Length: 351 a.a.        Molecular weight: 38306.34 Da        Isoelectric Point: 10.2305

>NTDB_id=621404 LK450_RS04810 WP_003032358.1 993496..994551(-) (sepM) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MEKPRNKFKKWPIIAVVGLILLFLSFVVPLPYYIEVPGGAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDITLKYLGVYVLQVTKNSTFKGILNIAGTVTGVN
DKTFNSSKDLIDYVGSQKIGSKVKVNYVEDGQKKSAIGKIIKLENGKNGIGISLIDRTEVTSNIPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS

Nucleotide


Download         Length: 1056 bp        

>NTDB_id=621404 LK450_RS04810 WP_003032358.1 993496..994551(-) (sepM) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
ATGGAAAAACCAAGAAATAAATTTAAAAAATGGCCGATAATTGCAGTAGTAGGGTTGATTTTGCTTTTCTTATCTTTTGT
AGTTCCCTTGCCTTATTATATTGAGGTGCCAGGTGGTGCAGCGGATGTCCGTCAGGTATTGCGCGTGGACAACAAAGAAG
ATAAGGAAAAAGGTTCTTATAATTTTGTAACGGTTGGAATTCAGCATGCGACCTTTGCTCATTTGGTTTATGCTTGGCTG
ACTCCTTTTACGGATATTTATTCGGCGAAAGATTTGACTGGTGGAACTTCTGATAAAGAATACATGCGGATCAATCAGTT
TTATATGGAAACGTCGCAAAACCTAGCTAAATACCAAGGGTTGAAAAAAGCTGGCAAAGACATTACTCTGAAATATCTAG
GGGTTTACGTCTTGCAAGTCACAAAGAATTCTACTTTTAAAGGTATTTTAAATATTGCAGGTACCGTGACAGGCGTGAAT
GATAAGACTTTCAACAGTTCAAAAGATTTGATTGATTATGTAGGCTCACAGAAAATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAAAAATCTGCTATAGGTAAAATTATCAAACTTGAAAATGGAAAAAATGGGATTGGTATTAGCT
TAATTGACCGAACAGAAGTCACAAGTAATATACCAATTGAATTTTCAACAGCAGGGATTGGTGGACCAAGTGCGGGCTTG
ATGTTTAGCTTGGCTATTTATACACAGATTGCAGACCCGACATTGAGAGATGGCAGAAATATTGCTGGGACAGGATCGAT
TGACCGTGAAGGAAAAGTTGGTGATATTGGTGGGATTGATAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTCACCAAGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAATTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAAAG
CACGAAAAAGTCGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(133-195)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(234-307)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3S4NJ72

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

63.93

97.151

0.621