Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   LK450_RS03660 Genome accession   NZ_CP085939
Coordinates   741126..742478 (-) Length   450 a.a.
NCBI ID   WP_003032751.1    Uniprot ID   A0A2I1UXL3
Organism   Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 736126..747478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK450_RS03645 (LK450_03645) rnc 738864..739562 (-) 699 WP_003032757.1 ribonuclease III -
  LK450_RS03650 (LK450_03650) - 739955..740312 (-) 358 Protein_724 YbaN family protein -
  LK450_RS03655 (LK450_03655) vicX 740321..741124 (-) 804 WP_003032665.1 MBL fold metallo-hydrolase Regulator
  LK450_RS03660 (LK450_03660) micB 741126..742478 (-) 1353 WP_003032751.1 cell wall metabolism sensor histidine kinase VicK Regulator
  LK450_RS03665 (LK450_03665) micA 742471..743172 (-) 702 WP_003025150.1 response regulator YycF Regulator
  LK450_RS03670 (LK450_03670) - 743466..743807 (-) 342 WP_003032667.1 hypothetical protein -
  LK450_RS03675 (LK450_03675) - 743834..745147 (-) 1314 WP_003032712.1 glycosyltransferase family 4 protein -
  LK450_RS03680 (LK450_03680) - 745149..746147 (-) 999 WP_022524413.1 glycosyltransferase family 4 protein -
  LK450_RS03685 (LK450_03685) ccpA 746327..747331 (-) 1005 WP_003032767.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51376.62 Da        Isoelectric Point: 4.6876

>NTDB_id=621392 LK450_RS03660 WP_003032751.1 741126..742478(-) (micB) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MIDNIRQFIVSKDFVFVLLILGFILVITLLSLENRRDNIRIRQLNQKVKDLIAGNYSEILDVQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDIEDEYDLRDLITKVPE
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTDTQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=621392 LK450_RS03660 WP_003032751.1 741126..742478(-) (micB) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
ATGATTGATAATATTAGACAATTTATTGTATCAAAAGACTTTGTATTTGTTTTACTTATTTTAGGGTTCATCTTGGTGAT
TACCTTGCTTTCCTTGGAAAATAGGCGAGACAATATTCGTATTCGCCAATTGAATCAAAAAGTAAAAGATTTAATTGCAG
GCAATTACTCAGAAATTTTAGATGTACAAGGTGGTCCAGAAATTACGGATATTACCAATAGTATCAATGATTTATCTGAG
GTAATCCGTCTAACGCATGAAAATTTAGAGCAAGAAACTAAGCGCCTGTCGAGTATTTTATCCTATATGACGGACGGTGT
TCTTGCGACCAATCGTCGTGGGCAGATTATCATGATCAATGATATGGCGACCAAGCAGTTGGGGGTCAAAGAATCCGAAG
CACGAAAGATGAATATCTTAAAACTGCTAGATATCGAAGACGAATATGACTTACGAGACTTGATTACGAAAGTTCCAGAG
TTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTCCGATTTGCCTTGATTCGTCGAGAATCTGG
CTTTATTTCAGGGCTGGTTGCGGTGCTGCACGATACAACGGAGCAGGAAAAAGAGGAGCGTGAGCGAAGACTGTTTGTTT
CGAATGTCAGTCACGAATTACGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCACTAGATGAAGGTGCCTTATCA
GAACCAGTCGCACCGGATTTCATCAAGGTTTCATTAGACGAGACCAATCGGATGATGCGCATGGTTTCGGACTTGCTGAG
TTTGTCACGTATTGACAATGCAACCAGTCATTTGGATATTGAATTGACGAATTTTACAGCTTTTATCACCTTTATTTTGA
ACCGTTTTGATAAAATCAGAAGCCAGAATGATGATAAAAAGTACGAAATTATCCGAGATTATCCGATTAACTCTATTTGG
GTCGAAATTGATACAGATAAGATGACACAGGTGATTGATAATATTATCAACAATGCCATTAAATATTCTCCTGACGGTGG
TAAAATTACGGTCAGTATGAAAACGACGGATACCCAAATGATTTTGTCGATTTCAGATGAAGGCTTAGGAATTCCTAAAA
AAGATTTGCCGAAAATTTTTGATAGATTTTATCGTGTAGACAAAGCAAGAAGTCGCGCACAAGGTGGATCCGGACTGGGC
TTAGCCATTGCCAAAGAGATTATCAAGCAGCATAACGGATTTATCTGGGCAAAGAGCGAGTACGGCAAAGGCTCGACGTT
TACAATCGTTCTGCCATATGACAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I1UXL3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

81.093

97.556

0.791
  vicK Streptococcus mutans UA159

71.883

90.889

0.653