Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   LK450_RS03665 Genome accession   NZ_CP085939
Coordinates   742471..743172 (-) Length   233 a.a.
NCBI ID   WP_003025150.1    Uniprot ID   A0A2I1UXK8
Organism   Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 737471..748172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK450_RS03645 (LK450_03645) rnc 738864..739562 (-) 699 WP_003032757.1 ribonuclease III -
  LK450_RS03650 (LK450_03650) - 739955..740312 (-) 358 Protein_724 YbaN family protein -
  LK450_RS03655 (LK450_03655) vicX 740321..741124 (-) 804 WP_003032665.1 MBL fold metallo-hydrolase Regulator
  LK450_RS03660 (LK450_03660) micB 741126..742478 (-) 1353 WP_003032751.1 cell wall metabolism sensor histidine kinase VicK Regulator
  LK450_RS03665 (LK450_03665) micA 742471..743172 (-) 702 WP_003025150.1 response regulator YycF Regulator
  LK450_RS03670 (LK450_03670) - 743466..743807 (-) 342 WP_003032667.1 hypothetical protein -
  LK450_RS03675 (LK450_03675) - 743834..745147 (-) 1314 WP_003032712.1 glycosyltransferase family 4 protein -
  LK450_RS03680 (LK450_03680) - 745149..746147 (-) 999 WP_022524413.1 glycosyltransferase family 4 protein -
  LK450_RS03685 (LK450_03685) ccpA 746327..747331 (-) 1005 WP_003032767.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26887.86 Da        Isoelectric Point: 4.6824

>NTDB_id=621393 LK450_RS03665 WP_003025150.1 742471..743172(-) (micA) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=621393 LK450_RS03665 WP_003025150.1 742471..743172(-) (micA) [Streptococcus anginosus subsp. anginosus strain FDAARGOS_1569]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACTGCCTTCGACGGTCGCGAAGCGTTAGAAATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTAA
TGTTGCCTGAAATGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGCAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGTGAGTTTGACAAAGTTATTGGTCTTGAGATTGGTGCAGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
GTTGCAGGCGCGTGTCAAAGCTATTTTGCGTCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTGCACCATTTGGCAACGCATATCGGACAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTGACAATTCGTCGTTTGAGAGAAAAGATAGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACGCGGCGCGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I1UXK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361