Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   N646_RS00235 Genome accession   NC_022349
Coordinates   54190..56445 (+) Length   751 a.a.
NCBI ID   WP_017820017.1    Uniprot ID   A0A2I3BYC1
Organism   Vibrio alginolyticus NBRC 15630 = ATCC 17749     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 49190..61445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N646_RS00210 (N646_0042) - 49549..50118 (-) 570 WP_017820014.1 hypothetical protein -
  N646_RS00215 (N646_0043) lolC 50368..51576 (+) 1209 WP_017820015.1 lipoprotein-releasing ABC transporter permease subunit LolC -
  N646_RS00220 (N646_0044) lolD 51569..52276 (+) 708 WP_005378457.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  N646_RS00225 (N646_0045) lolE 52279..53523 (+) 1245 WP_017820016.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  N646_RS00230 (N646_0046) - 53672..54181 (-) 510 WP_005387834.1 DUF2062 domain-containing protein -
  N646_RS00235 (N646_0047) comEC 54190..56445 (+) 2256 WP_017820017.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  N646_RS00240 (N646_0048) msbA 56477..58225 (+) 1749 WP_017820018.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  N646_RS00245 (N646_0049) lpxK 58231..59238 (+) 1008 WP_017820019.1 tetraacyldisaccharide 4'-kinase -
  N646_RS00250 (N646_0050) - 59219..59398 (+) 180 WP_005378451.1 Trm112 family protein -
  N646_RS00255 (N646_0051) kdsB 59398..60153 (+) 756 WP_017820020.1 3-deoxy-manno-octulosonate cytidylyltransferase -

Sequence

Protein


Download         Length: 751 a.a.        Molecular weight: 84331.22 Da        Isoelectric Point: 8.3254

>NTDB_id=62015 N646_RS00235 WP_017820017.1 54190..56445(+) (comEC) [Vibrio alginolyticus NBRC 15630 = ATCC 17749]
MTLSEKSWTLALFVASVISSAWWPTIPDWRWLLLGIITTGSIIKLRRGLISIGAIAGFMVVIVHGNVLESQRQALFQAGE
NITIIGKVDSPFTQISHGYEGIVAIEAVNSQTLLPFLKPKIRLITPFPLDVNSEFTTSISLKPITGLRNEAGFDAEKHAM
GKNIIARAVVNKDAKWIVRSNVSLRQSIIADVADDVSSLHHFSLISALVFADRSWLSKEDWQALRDSGLLHLVSISGLHI
GMAFTFGLVVGGTVRYLLPQYQLLPSLYGLIFAVAYAWLADFSLPTTRAVSVCVVYVLLKYTLVHWTSWRVLLLAVSLQL
LVQPFASYSMSFWLSYLSVCAVLFAINLIRHQRGGWKERLKALLLTQLMLSALIVPVSGHFFSGFSLSSIAYNLVFIPWF
GFIVVPLMFLALFSSLFLEVIAKPLWHSVDWSLQPLSTSIQYAIGSWQPISMEMTMLVMAIVVCLIFQRFMSQYAWYLLL
GIVISIKLASEYEPHWRIDVLDVGHGLAVVVEKDDKVLLYDTGKAWQSGSIAEQVVTPVLHQRGYESIDTLILSHFDNDH
AGGRFFIEDAFSPQRKLSSQFFIGYEPCTRGDQWKWQGLNMEVLWPPALVQRAYNPHSCVLRLTDPISNFSMLFTGDIEA
ISEWILLREPGKLQSDVVLVPHHGSKSSSNPRFIEAVSPSVAVASLAKNNRWGMPAESVVASYRKLGITWLDTGEGGQVS
FFIHRDNWRSETKRSDTFEPWYRQMLRKGVE

Nucleotide


Download         Length: 2256 bp        

>NTDB_id=62015 N646_RS00235 WP_017820017.1 54190..56445(+) (comEC) [Vibrio alginolyticus NBRC 15630 = ATCC 17749]
ATGACTCTCTCAGAAAAAAGTTGGACCTTGGCGTTATTTGTAGCGAGCGTAATCTCGTCAGCTTGGTGGCCGACAATACC
AGATTGGCGTTGGTTGCTGCTGGGAATAATAACCACTGGCTCAATAATCAAATTACGTCGTGGCTTAATTAGCATAGGCG
CAATTGCGGGCTTTATGGTTGTCATCGTCCACGGCAATGTATTGGAGTCTCAGAGACAAGCCCTTTTTCAAGCAGGGGAG
AATATTACCATAATTGGTAAAGTTGACAGCCCTTTTACGCAAATAAGTCACGGTTATGAAGGTATTGTCGCTATAGAAGC
GGTAAATTCTCAAACTCTGTTACCTTTTCTTAAACCTAAAATCCGTCTTATTACGCCTTTTCCACTCGATGTTAACAGTG
AGTTTACGACATCCATCTCGTTAAAGCCGATTACAGGTCTACGCAACGAAGCTGGCTTTGATGCTGAAAAGCACGCGATG
GGTAAAAATATTATCGCCCGAGCGGTTGTCAACAAAGACGCTAAGTGGATTGTTCGTTCTAATGTATCTCTGCGTCAATC
CATTATTGCCGATGTCGCTGATGATGTGTCTTCCCTTCATCATTTCTCGTTAATAAGTGCGTTAGTTTTTGCTGACCGTT
CTTGGTTGTCTAAGGAAGATTGGCAAGCGCTCAGGGACAGTGGTTTACTGCATTTGGTCTCCATTTCTGGTTTACATATT
GGTATGGCGTTTACTTTTGGGCTAGTCGTGGGCGGTACCGTTCGTTATCTATTACCCCAATACCAGTTGTTACCTAGCTT
ATATGGGCTGATCTTCGCTGTTGCCTACGCTTGGTTAGCGGATTTCTCTCTGCCTACTACGCGAGCAGTGTCGGTATGCG
TTGTTTACGTTCTCCTGAAGTATACTCTGGTGCACTGGACTTCTTGGCGAGTTCTTTTGCTTGCAGTATCTCTACAACTG
CTTGTCCAACCTTTTGCATCCTACAGTATGAGCTTTTGGTTATCGTACCTCTCCGTTTGTGCGGTATTGTTCGCAATTAA
TTTGATTCGACATCAAAGGGGAGGTTGGAAAGAGCGATTAAAAGCGTTATTGCTTACTCAATTGATGTTGAGCGCTTTAA
TCGTACCTGTTAGTGGCCATTTCTTCTCCGGTTTTAGTTTGTCCTCAATAGCCTACAACTTGGTATTTATTCCTTGGTTC
GGATTTATCGTTGTACCTTTGATGTTTCTAGCCCTGTTCTCATCTTTGTTTCTTGAAGTGATAGCGAAGCCTCTGTGGCA
TTCGGTGGACTGGTCATTACAGCCATTGAGCACGTCAATACAGTACGCAATAGGTTCTTGGCAACCTATTAGCATGGAAA
TGACAATGCTGGTTATGGCGATAGTGGTTTGCTTAATATTTCAACGGTTCATGTCTCAGTACGCGTGGTATTTGTTACTC
GGCATCGTTATTAGTATCAAGCTTGCATCGGAGTATGAACCGCATTGGCGTATCGATGTATTAGATGTAGGTCATGGCCT
TGCAGTGGTTGTAGAAAAAGACGACAAGGTGTTGCTGTATGACACTGGTAAAGCATGGCAAAGCGGCAGTATCGCAGAGC
AGGTCGTCACTCCGGTTTTGCATCAACGAGGTTATGAAAGCATAGATACACTGATTCTAAGCCATTTCGATAATGATCAC
GCAGGCGGCCGCTTTTTCATTGAAGATGCCTTTTCTCCACAGCGTAAACTTAGTAGTCAATTCTTTATCGGATATGAGCC
TTGCACTAGAGGTGACCAATGGAAATGGCAAGGATTAAACATGGAAGTGCTCTGGCCTCCTGCACTTGTTCAACGTGCGT
ATAATCCGCACTCCTGTGTATTACGACTTACTGACCCTATTTCTAACTTTAGTATGCTTTTTACTGGTGATATTGAGGCC
ATTAGCGAGTGGATTTTGCTTAGAGAACCCGGAAAGTTACAAAGCGATGTGGTGCTAGTCCCTCACCACGGGAGTAAAAG
TTCATCGAATCCTCGATTTATCGAGGCGGTGAGCCCGAGTGTGGCGGTTGCTTCTTTAGCAAAAAACAATCGATGGGGAA
TGCCAGCGGAAAGTGTCGTTGCTTCATACCGAAAGCTTGGCATTACTTGGCTTGATACTGGTGAGGGTGGTCAGGTAAGC
TTCTTTATTCACCGTGATAATTGGCGCTCAGAAACCAAACGTAGCGATACATTTGAGCCTTGGTATAGGCAGATGCTGCG
TAAGGGAGTAGAATGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(208-465)

Metallo-beta-lactamase superfamily (Lactamase_B)

(503-684)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I3BYC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio parahaemolyticus RIMD 2210633

69.016

100

0.691
  comEC Vibrio campbellii strain DS40M4

65.559

100

0.656
  comEC Vibrio cholerae strain A1552

43.501

100

0.437

Multiple sequence alignment