Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NW339_RS00165 Genome accession   NZ_CP102947
Coordinates   30195..30785 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain SCAID WND1-2022 (119)     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 25195..35785
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW339_RS00140 (NW339_00140) ysdE 26280..26354 (+) 75 WP_211180519.1 protein YsdE -
  NW339_RS00145 (NW339_00145) ivbL 26599..26697 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  NW339_RS00150 (NW339_00150) ilvB 26803..28491 (+) 1689 WP_000168502.1 acetolactate synthase large subunit -
  NW339_RS00155 (NW339_00155) ilvN 28495..28785 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  NW339_RS25815 - 28851..29711 (-) 861 Protein_31 DUF6708 domain-containing protein -
  NW339_RS00165 (NW339_00165) letA 30195..30785 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  NW339_RS00170 (NW339_00170) uhpB 30785..32287 (+) 1503 WP_001304997.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NW339_RS00175 (NW339_00175) uhpC 32297..33616 (+) 1320 WP_001296565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NW339_RS00180 (NW339_00180) uhpT 33754..35145 (+) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=618873 NW339_RS00165 WP_000633668.1 30195..30785(+) (letA) [Escherichia coli strain SCAID WND1-2022 (119)]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=618873 NW339_RS00165 WP_000633668.1 30195..30785(+) (letA) [Escherichia coli strain SCAID WND1-2022 (119)]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCTGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACAGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378