Detailed information
Bioinformatically predicted
Overview
| Name | sepM | Type | Regulator |
| Locus tag | SCR2_RS02250 | Genome accession | NC_022245 |
| Coordinates | 437963..439018 (+) | Length | 351 a.a. |
| NCBI ID | WP_020997642.1 | Uniprot ID | U2ZNX3 |
| Organism | Streptococcus constellatus subsp. pharyngis C818 | ||
| Function | processing of CSP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 434175..444243 | 437963..439018 | within | 0 |
Gene organization within MGE regions
Location: 434175..444243
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SCR2_RS02225 (SCR2_0442) | comFA/cflA | 434175..435476 (+) | 1302 | WP_020997640.1 | DEAD/DEAH box helicase | Machinery gene |
| SCR2_RS02230 (SCR2_0443) | - | 435473..436138 (+) | 666 | WP_006267632.1 | ComF family protein | - |
| SCR2_RS02235 (SCR2_0444) | hpf | 436217..436759 (+) | 543 | WP_006267638.1 | ribosome hibernation-promoting factor, HPF/YfiA family | - |
| SCR2_RS02240 (SCR2_0445) | rsmD | 436956..437495 (+) | 540 | WP_020997641.1 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD | - |
| SCR2_RS02245 (SCR2_0446) | coaD | 437485..437982 (+) | 498 | WP_006267255.1 | pantetheine-phosphate adenylyltransferase | - |
| SCR2_RS02250 (SCR2_0447) | sepM | 437963..439018 (+) | 1056 | WP_020997642.1 | SepM family pheromone-processing serine protease | Regulator |
| SCR2_RS02255 (SCR2_0448) | - | 439305..439862 (+) | 558 | WP_006267391.1 | YutD family protein | - |
| SCR2_RS02260 (SCR2_0449) | rlmN | 439896..440978 (+) | 1083 | WP_006269861.1 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | - |
| SCR2_RS02265 (SCR2_0450) | - | 440971..441489 (+) | 519 | WP_003070167.1 | VanZ family protein | - |
| SCR2_RS02270 (SCR2_0451) | cclA/cilC | 441484..442158 (-) | 675 | WP_020997643.1 | prepilin peptidase | Machinery gene |
| SCR2_RS02275 (SCR2_0452) | - | 442309..442836 (+) | 528 | WP_006267546.1 | Dps family protein | - |
| SCR2_RS02280 (SCR2_0454) | - | 443053..444243 (-) | 1191 | WP_006267506.1 | site-specific integrase | - |
Sequence
Protein
Download Length: 351 a.a. Molecular weight: 38352.39 Da Isoelectric Point: 10.2387
>NTDB_id=61809 SCR2_RS02250 WP_020997642.1 437963..439018(+) (sepM) [Streptococcus constellatus subsp. pharyngis C818]
MEKSRTKFKKWPIVAVVGLLLLFMSFIVPLPYYIEVPGGAADVRQVLRVDNKVDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDISLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKDLIDYVGSQKIGSKVKVNYVEDGHKKSAIGKIIKLENGKNGIGISLIDRTEVTSNIPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTREVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS
MEKSRTKFKKWPIVAVVGLLLLFMSFIVPLPYYIEVPGGAADVRQVLRVDNKVDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDISLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKDLIDYVGSQKIGSKVKVNYVEDGHKKSAIGKIIKLENGKNGIGISLIDRTEVTSNIPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTREVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS
Nucleotide
Download Length: 1056 bp
>NTDB_id=61809 SCR2_RS02250 WP_020997642.1 437963..439018(+) (sepM) [Streptococcus constellatus subsp. pharyngis C818]
ATGGAAAAATCACGAACTAAATTTAAAAAATGGCCGATAGTGGCTGTAGTAGGGCTGCTTCTACTGTTCATGTCTTTTAT
AGTTCCTCTGCCTTATTACATTGAGGTGCCAGGTGGTGCAGCAGATGTTCGGCAAGTATTACGTGTAGATAATAAAGTGG
ATAAGGAAAAAGGTTCTTATAACTTTGTCACTGTTGGGATTCAGCATGCAACCTTTGCTCATTTGGTTTATGCTTGGTTG
ACTCCTTTTACAGATATTTATTCGGCGAAAGATCTGACTGGCGGAACTTCTGATAAAGAATATATGCGAATCAATCAATT
TTATATGGAAACATCACAAAACTTAGCCAAATATCAAGGGTTAAAAAAAGCAGGCAAGGATATTAGCTTGAAATATTTGG
GTGTTTATGTGTTGCAAGTTACCAAGAATTCAACCTTTAAAGGGATTCTAAATATTGCAGATACTGTGACAGGCGTGAAT
GATAAGACTTTCAACAGTTCAAAAGATTTGATTGATTATGTAGGCTCACAGAAAATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCATAAAAAATCTGCTATAGGTAAAATTATCAAACTTGAAAATGGGAAAAATGGAATTGGTATTAGCT
TAATTGACCGAACAGAAGTCACAAGTAATATACCAATTGAATTTTCAACAGCTGGGATTGGTGGACCAAGTGCGGGTTTG
ATGTTTAGCTTGGCGATTTATACACAGATTGCAGACCCGACATTGAGAGATGGCAGAAATATTGCTGGGACAGGATCGAT
TGACCGTGAAGGAAAAGTTGGTGATATTGGTGGGATTGATAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTTACCAGGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAATTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAAAG
TACTAAAAAATCTTAA
ATGGAAAAATCACGAACTAAATTTAAAAAATGGCCGATAGTGGCTGTAGTAGGGCTGCTTCTACTGTTCATGTCTTTTAT
AGTTCCTCTGCCTTATTACATTGAGGTGCCAGGTGGTGCAGCAGATGTTCGGCAAGTATTACGTGTAGATAATAAAGTGG
ATAAGGAAAAAGGTTCTTATAACTTTGTCACTGTTGGGATTCAGCATGCAACCTTTGCTCATTTGGTTTATGCTTGGTTG
ACTCCTTTTACAGATATTTATTCGGCGAAAGATCTGACTGGCGGAACTTCTGATAAAGAATATATGCGAATCAATCAATT
TTATATGGAAACATCACAAAACTTAGCCAAATATCAAGGGTTAAAAAAAGCAGGCAAGGATATTAGCTTGAAATATTTGG
GTGTTTATGTGTTGCAAGTTACCAAGAATTCAACCTTTAAAGGGATTCTAAATATTGCAGATACTGTGACAGGCGTGAAT
GATAAGACTTTCAACAGTTCAAAAGATTTGATTGATTATGTAGGCTCACAGAAAATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCATAAAAAATCTGCTATAGGTAAAATTATCAAACTTGAAAATGGGAAAAATGGAATTGGTATTAGCT
TAATTGACCGAACAGAAGTCACAAGTAATATACCAATTGAATTTTCAACAGCTGGGATTGGTGGACCAAGTGCGGGTTTG
ATGTTTAGCTTGGCGATTTATACACAGATTGCAGACCCGACATTGAGAGATGGCAGAAATATTGCTGGGACAGGATCGAT
TGACCGTGAAGGAAAAGTTGGTGATATTGGTGGGATTGATAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTTACCAGGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAATTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAAAG
TACTAAAAAATCTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| sepM | Streptococcus mutans UA159 |
63.372 |
98.006 |
0.621 |