Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   LIS75_RS05720 Genome accession   NZ_CP085388
Coordinates   1103733..1104389 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain CMF18     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1098733..1109389
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIS75_RS05690 (LIS75_05705) oppF 1099259..1100176 (+) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -
  LIS75_RS05695 (LIS75_05710) - 1100286..1101473 (+) 1188 WP_003155036.1 putative glycoside hydrolase -
  LIS75_RS05700 (LIS75_05715) - 1101591..1102169 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  LIS75_RS05705 (LIS75_05720) spx 1102348..1102743 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  LIS75_RS05710 (LIS75_05725) - 1102801..1103457 (-) 657 WP_057080091.1 TerC family protein -
  LIS75_RS05720 (LIS75_05730) mecA 1103733..1104389 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  LIS75_RS05725 (LIS75_05735) - 1104540..1105700 (+) 1161 WP_252206747.1 competence protein CoiA family protein -
  LIS75_RS05730 (LIS75_05740) pepF 1105928..1107757 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  LIS75_RS05735 (LIS75_05745) - 1107795..1107962 (-) 168 WP_003155026.1 hypothetical protein -
  LIS75_RS05740 (LIS75_05750) spxH 1108248..1109150 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=617266 LIS75_RS05720 WP_003155032.1 1103733..1104389(+) (mecA) [Bacillus velezensis strain CMF18]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=617266 LIS75_RS05720 WP_003155032.1 1103733..1104389(+) (mecA) [Bacillus velezensis strain CMF18]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895