Detailed information
Bioinformatically predicted
Overview
| Name | pilE | Type | Machinery gene |
| Locus tag | NGFG_RS11555 | Genome accession | NC_022240 |
| Coordinates | 2123867..2124289 (-) | Length | 140 a.a. |
| NCBI ID | WP_080229175.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae MS11 | ||
| Function | assembly of type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 2120757..2142492 | 2123867..2124289 | within | 0 |
Gene organization within MGE regions
Location: 2120757..2142492
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NGFG_RS11540 (NGFG_00010) | - | 2120757..2121971 (-) | 1215 | WP_003694614.1 | replication initiation factor domain-containing protein | - |
| NGFG_RS15340 | - | 2122673..2123038 (-) | 366 | Protein_2163 | pilin | - |
| NGFG_RS16200 | - | 2123078..2123485 (-) | 408 | Protein_2164 | pilin | - |
| NGFG_RS11555 (NGFG_02487) | pilE | 2123867..2124289 (-) | 423 | WP_080229175.1 | pilin | Machinery gene |
| NGFG_RS14890 | - | 2124315..2124662 (-) | 348 | Protein_2166 | pilin | - |
| NGFG_RS16205 | - | 2124702..2125046 (-) | 345 | Protein_2167 | pilin | - |
| NGFG_RS16680 | - | 2125161..2125298 (-) | 138 | Protein_2168 | pilin | - |
| NGFG_RS15345 | - | 2125672..2125803 (-) | 132 | WP_010356054.1 | hypothetical protein | - |
| NGFG_RS11575 (NGFG_00016) | - | 2125885..2126573 (-) | 689 | Protein_2170 | SprT family zinc-dependent metalloprotease | - |
| NGFG_RS11580 (NGFG_00017) | - | 2126570..2127313 (-) | 744 | WP_003687014.1 | lysophospholipid acyltransferase family protein | - |
| NGFG_RS11585 (NGFG_00018) | gmhB | 2127343..2127906 (-) | 564 | WP_003687015.1 | D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase | - |
| NGFG_RS11590 (NGFG_00019) | - | 2128049..2129712 (+) | 1664 | Protein_2173 | LTA synthase family protein | - |
| NGFG_RS16215 | - | 2129779..2130237 (-) | 459 | Protein_2174 | glycosyltransferase family 4 protein | - |
| NGFG_RS11595 (NGFG_00020) | - | 2130135..2130833 (-) | 699 | WP_025455756.1 | glycosyltransferase family 4 protein | - |
| NGFG_RS11600 (NGFG_00021) | - | 2130985..2132226 (-) | 1242 | WP_003694622.1 | aromatic amino acid transporter | - |
| NGFG_RS11605 (NGFG_00022) | ubiG | 2132374..2133102 (+) | 729 | WP_003694623.1 | bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG | - |
| NGFG_RS11610 (NGFG_00023) | thrB | 2133139..2134056 (+) | 918 | WP_003692348.1 | homoserine kinase | - |
| NGFG_RS11615 (NGFG_00024) | - | 2134242..2134760 (-) | 519 | WP_003687025.1 | gluconokinase, GntK/IdnK-type | - |
| NGFG_RS11620 (NGFG_00025) | - | 2134780..2136165 (-) | 1386 | WP_003694624.1 | GntP family permease | - |
| NGFG_RS11625 (NGFG_00027) | - | 2136556..2138097 (+) | 1542 | WP_020997419.1 | ABC transporter permease | - |
| NGFG_RS11630 (NGFG_00028) | - | 2138126..2138725 (+) | 600 | WP_003687033.1 | beta-class carbonic anhydrase | - |
| NGFG_RS11635 (NGFG_00029) | nadD | 2138722..2139327 (+) | 606 | WP_003694625.1 | nicotinate-nucleotide adenylyltransferase | - |
| NGFG_RS11640 (NGFG_00030) | rsfS | 2139386..2139772 (+) | 387 | WP_003687037.1 | ribosome silencing factor | - |
| NGFG_RS11645 (NGFG_00031) | rlmH | 2139825..2140295 (+) | 471 | WP_003690383.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| NGFG_RS11650 (NGFG_00032) | - | 2140369..2140635 (+) | 267 | WP_002214948.1 | oxidative damage protection protein | - |
| NGFG_RS11655 (NGFG_00033) | - | 2140792..2141475 (+) | 684 | WP_003687040.1 | Bax inhibitor-1/YccA family protein | - |
| NGFG_RS11660 (NGFG_00034) | coaD | 2141605..2142120 (+) | 516 | WP_003692360.1 | pantetheine-phosphate adenylyltransferase | - |
Sequence
Protein
Download Length: 140 a.a. Molecular weight: 14914.88 Da Isoelectric Point: 10.0070
>NTDB_id=61723 NGFG_RS11555 WP_080229175.1 2123867..2124289(-) (pilE) [Neisseria gonorrhoeae MS11]
MSNTSKKSAVAGYCPNHGTWPKDNGDAGVASPADKIKGKYVQKVEVAKGVVTAEMASTGVNKEIKDKKLSLWAKRQDGSV
KWFCGQPVTRGAGNAGKADDVTKAGNDNEKINTKHLPSTCRDKSTAICIETPPTAFYKNT
MSNTSKKSAVAGYCPNHGTWPKDNGDAGVASPADKIKGKYVQKVEVAKGVVTAEMASTGVNKEIKDKKLSLWAKRQDGSV
KWFCGQPVTRGAGNAGKADDVTKAGNDNEKINTKHLPSTCRDKSTAICIETPPTAFYKNT
Nucleotide
Download Length: 423 bp
>NTDB_id=61723 NGFG_RS11555 WP_080229175.1 2123867..2124289(-) (pilE) [Neisseria gonorrhoeae MS11]
ATTTCAAACACTTCCAAAAAATCAGCCGTTGCCGGGTATTGCCCGAATCACGGCACATGGCCGAAAGACAACGGTGATGC
CGGCGTGGCATCCCCCGCCGACAAAATCAAAGGCAAATATGTTCAGAAAGTTGAAGTCGCAAAAGGCGTCGTTACCGCCG
AAATGGCTTCAACCGGCGTAAACAAAGAAATCAAAGACAAAAAACTCTCCCTGTGGGCCAAGCGTCAAGACGGTTCGGTA
AAATGGTTCTGCGGACAGCCGGTTACGCGCGGCGCCGGCAACGCCGGCAAAGCCGACGACGTCACCAAAGCCGGCAACGA
CAACGAAAAAATCAACACCAAGCACCTGCCGTCAACCTGCCGCGATAAATCAACTGCCATTTGCATAGAAACACCACCTA
CGGCTTTCTATAAAAATACCTAA
ATTTCAAACACTTCCAAAAAATCAGCCGTTGCCGGGTATTGCCCGAATCACGGCACATGGCCGAAAGACAACGGTGATGC
CGGCGTGGCATCCCCCGCCGACAAAATCAAAGGCAAATATGTTCAGAAAGTTGAAGTCGCAAAAGGCGTCGTTACCGCCG
AAATGGCTTCAACCGGCGTAAACAAAGAAATCAAAGACAAAAAACTCTCCCTGTGGGCCAAGCGTCAAGACGGTTCGGTA
AAATGGTTCTGCGGACAGCCGGTTACGCGCGGCGCCGGCAACGCCGGCAAAGCCGACGACGTCACCAAAGCCGGCAACGA
CAACGAAAAAATCAACACCAAGCACCTGCCGTCAACCTGCCGCGATAAATCAACTGCCATTTGCATAGAAACACCACCTA
CGGCTTTCTATAAAAATACCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilE | Neisseria gonorrhoeae strain FA1090 |
73.554 |
86.429 |
0.636 |
| pilE | Neisseria gonorrhoeae MS11 |
61.667 |
85.714 |
0.529 |