Detailed information NTG0616903

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: LJA36_RS12110
• Genome accession: NZ_CP085282
• Coordinates: 2545360..2546523 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus amyloliquefaciens strain TPS17
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2540360..2551523

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LJA36_RS12090	-	2540776..2541963 (+)	1188	WP_113792227.1	glycosyltransferase	-
LJA36_RS12095	-	2542105..2543181 (+)	1077	WP_003151382.1	MraY family glycosyltransferase	-
LJA36_RS12100	-	2543271..2544485 (-)	1215	WP_015418337.1	LCP family protein	-
LJA36_RS12105	-	2544490..2545137 (-)	648	WP_003151384.1	YigZ family protein	-
LJA36_RS12110	degS	2545360..2546523 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
LJA36_RS12115	degU	2546600..2547289 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
LJA36_RS12120	-	2547387..2548235 (+)	849	WP_015418336.1	DegV family protein	-
LJA36_RS12125	comFA	2548343..2549728 (+)	1386	WP_040238815.1	DEAD/DEAH box helicase	Machinery gene
LJA36_RS12130	-	2549786..2550070 (+)	285	WP_003151389.1	competence protein ComFB	-
LJA36_RS12135	comFC	2550076..2550765 (+)	690	WP_199776864.1	phosphoribosyltransferase family protein	Machinery gene
LJA36_RS12140	-	2550839..2551258 (+)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=616903 LJA36_RS12110 WP_007407484.1 2545360..2546523(+) (degS) [Bacillus amyloliquefaciens strain TPS17]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=616903 LJA36_RS12110 WP_007407484.1 2545360..2546523(+) (degS) [Bacillus amyloliquefaciens strain TPS17]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951