Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NUI00_RS02900 Genome accession   NZ_CP102488
Coordinates   641401..642057 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O15:H18 strain ST69     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 636401..647057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NUI00_RS02870 (NUI00_02870) dcyD 637280..638266 (+) 987 WP_001128228.1 D-cysteine desulfhydrase -
  NUI00_RS02875 (NUI00_02875) tcyL 638281..638949 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NUI00_RS02880 (NUI00_02880) tcyN 638946..639698 (+) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NUI00_RS02885 (NUI00_02885) sdiA 639928..640650 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  NUI00_RS02890 (NUI00_02890) yecF 640718..640942 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NUI00_RS02895 (NUI00_02895) yecU 640929..641105 (-) 177 WP_000590347.1 protein YecU -
  NUI00_RS02900 (NUI00_02900) letA 641401..642057 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NUI00_RS02905 (NUI00_02905) uvrC 642054..643886 (+) 1833 WP_115763450.1 excinuclease ABC subunit UvrC Machinery gene
  NUI00_RS02910 (NUI00_02910) pgsA 643943..644491 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NUI00_RS02930 (NUI00_02930) yecA 645141..645806 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=616623 NUI00_RS02900 WP_000611328.1 641401..642057(+) (letA) [Escherichia coli O15:H18 strain ST69]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=616623 NUI00_RS02900 WP_000611328.1 641401..642057(+) (letA) [Escherichia coli O15:H18 strain ST69]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482